“…During the last few decades, considerable attention has been devoted to synthesis of 1,2,4-triazole derivatives possessing such comprehensive bioactivities as antibacterial, antifungal (Karabasanagouda et al, 2007;Sztanke et al, 2008), antimycobacterial (Klimesová et al, 2004), anti-inflammatory (Mullican et al, 1993), analgesic (Tozkoparan et al, 2005), anticancer (Demirba et al, 2002), antihypertensive (Kakefuda et al, 2002), anticonvulsant (Küçükgüzel et al, 2004), antiviral (El-Essawy et al, 2008), antidepressant (Kane et al, 1988), antiasthmatic (Youichiro et al, 1996), diuretic (Mhasalkar et al, 1970) and hypoglycemic (Blank et al, 1972) activities.…”