Abstract:The chemical manipulation of the aminosucrar, daunosamine, has resulted in the development of new interesting doxorubicin analogues, namely 4'-epi-and 4'-deoxydoxorubicin, whereas the total synthesis of new aglycones has Drovided new structural types of the anthracyclines. In the field of beta-lactams, efforts aimed to the discovery of original anti-infective compounds have led to the synthesis of novel "penem" derivatives starting from methyl penicillinate.In this paper I shall deal with two major lines of in… Show more
Review: Übersicht über die in der Arbeitsgruppe des Autors behandelten Projekte (Entwicklung neuer Antitumor‐Anthracycline und neuartiger bioaktiver β‐Lactam‐Derivate).
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