Synthesis,Herbicidal Activities of Novel Triketone Compounds Containing 4-Substituted Cyclopentane-1,3-dione Moiety

Abstract

To find new lead compounds with muti-bioactivities, a series of novel triketone derivatives containing 4-substituted cyclopentane-1,3-dione were designed on the base of various commercial products. The target compounds were synthesized from cyclopentane-1,3-dione in six steps. Their structures were confirmed by IR, 1 H NMR spectra and HRMS. The preliminary greenhouse bioassay results indicated that some compounds showed obvious inhibition effects against Brassica campestris, and the inhibition rate was more than 80% at 100 μg/mL. In the pre-and post-emergence, some of them exhibited excellent herbicidal activities against Brassica campestris, and the herbicidal activity was more than 90% at 1500 g/ha.