Synthesis, fungicidal activity and SAR of new amino acid derivatives containing substituted 1-(phenylthio)propan-2-amine moiety

Isolation, Synthesis, and Fungicidal Activity of Isopropyl (3-methyl-1-oxo-1-((1-((4-(prop-2-yn-1-yloxy)phenyl)thio)propan-2-yl)amino)butan-2-yl)carbamate Diastereomers against Phytophthora capsici

“…In our previous work, some amino acid analogues [12][13][14][15][16][17] were designed and synthesized, including isopropyl (3-methyl-1-oxo-1-((1-((4-(prop-2-yn-1-yloxy)phenyl)thio) propan-2-yl)amino)butan-2-yl)carbamate diastereomers, which possessed good fungicidal activity. In this paper, isopropyl (3-methyl-1-oxo-1-((1-((4-(prop-2-yn-1-yloxy) phenyl)thio)propan-2-yl)amino)butan-2-yl)carbamate diastereomers were used as starting materials and their racemate was isolated.…”