Synthesis, Fluorescence Properties and Biological Activity of 8‐Hydroxyquinoline Conjugate Bonded Aromatic Heterocyclic Derivatives

Abstract

Four kinds of 8-hydroxyquinoline conjugate bonded aromatic heterocyclic derivatives were designed and synthesized for potential use in the emission and electron conduction layers in organic light emitting devices, and as luminescent probes for metal ions. These novel compounds were characterized by IR, 1 H NMR, 13 C NMR, Mass and UV-visible spectra. The photoluminescent properties of the new compounds including the spectra (shape of bands, λ ex , λ em ), quantum yield (φ f ) and lifetime (τ) were investigated. Moreover, density functional theory method was used to study the relationship between the geometric configuration and emission wavelength. MTT assays of cell proliferation of rMSC and DPPH radical-scavenging tests suggested that the new compounds generate a significant increase of rMSC and demonstrate a good antioxidant activity.

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“…Another attractive feature of the planner structure of 8HQ derivatives is their luminescence properties, which facilitate their application as a potent luminescent probe or an organic light-emitting device (Wei, Zeng, Xu, & Liu, 2008).…”