Synthesis, electrochemical, structural and theoretical study of new derivatives of O B N and O B O heterocycles

Boron-Based Inhibitors of the NLRP3 Inflammasome

“…The R factors obtained for NBC6 and NBC11 were 4.08% and 2.83%, respectively. The B atom lies out of the ring plane in a boat-envelope conformation in both oxazaborine structures, whereas the other atoms in the heterocycle are planar and are involved in a π-electron conjugated system ( Figure 4 A) as previously reported for other oxazaborines ( Josefíka et al., 2012 , Mikyseka et al., 2017 ). NBC6 is chelated to B through O/N chelation of the amide C=O and enamine NH ( Figure 4 A), whereas NBC11 is chelated to B through O/N chelation of the ketone C=O and enamine NH ( Figure 4 B).…”

Molecular structure and intramolecular hydrogen bond strength of 3-methyl-4-amino-3-penten-2-one and its N Me and N-Ph substitutions by experimental and theoretical methods

“…This compound was prepared according to a procedure similar to that described for APO [28]. This compound was synthesized by modification of a literature method [30,31]. To a solution of α-methyl acetylacetone (1.23 g, 11.0 mmol) in absolute ethyl alcohol (10 ml) was added a 2M solution of methylamine in THF (10 ml, 20 mmol) and the clear solution was stirred at room temperature in a stoppered flask for 15 hrs.…”

Fluorescence Quenching in BODIPY Dyes: The Role of Intramolecular Interactions and Charge Transfer

“…, was only reported in 2009), followed by an extensive synthetic efforts to functionalize the dye core and tune the chemical and photophysical properties . Alternatively, the success of BODIPY derivatives inspired the design of various similar compounds such as aza‐BODIPY, PODIPY, BODIHY, BOPHY, BOIMPY and others …”