Synthesis, crystallographic studies, high resolution mass spectrometric analyses and antibacterial assays of silver(I) complexes with sulfisoxazole and sulfadimethoxine

Antifungal, phyto, cyto, genotoxic and lipophilic properties of three complexes of sulfadimethoxine (HSDM) with Ag(I). Synthesis and characterization of [Ag3SDM(SCN)2]·H2O and [Ag2(SDM)2o-phenanthroline]·H2O

“…Yield: 94 %. These data are consistent with those reported by Dubey et al, 2018 [7] and Fiori et al, 2017 [8]. AgSDM-SCN: in a typical experience, 2 mL of aqueous solution of 1.1 mmol of silver nitrate was added dropwise to 4 mL of stirring aqueous solution containing 1 mmol of NaSDM.…”

“…It is most frequently used in veterinary medicine, although it is approved in some countries for human use [6]. Recently, the crystalline structure of the homoleptic complex of silver with sulfadimethoxine, AgSDM, has been determined, both in aqueous [7,8] and organic medium [9]. The antibacterial properties [7,8] and DNA interaction [9] of AgSDM were determined, but not its antifungal properties.…”

A Silver Complex with Cycloserine: Synthesis, Spectroscopic Characterization, Crystal Structure and In Vitro Biological Studies

“…This behavior may be due to the fast release of silver ions from silver nitrate, as already described in the literature . Although more effective than AgCIC, silver nitrate is light sensitive and is also toxic to human tissues in concentrations higher than 1%, which have limited it use ,…”

Structure, Antimicrobial Activity, Hirshfeld Analysis, and Docking Studies of Three Silver(I) Complexes-Based Pyridine Ligands

“…Silver-containing compounds continue to attract academic attention for their antimicrobial properties [1][2][3][4][5][6][7][8] but also for the immense variety of its coordination polymers, [9] and sometimes the two coincide [10]. A recent review is optimistic of the future role of silver in medicine, [11] while clinical studies are still not of sufficient quality to judge the practical usefulness of different silver based wound healing materials, the most common medical application [12].…”