Synthesis, crystal structures, DNA interaction and anticancer activity of organobismuth(V) complexes

Structural Diversity of Bismuth(III) Thiophenemonocarboxylates Isolated from Aqueous Solutions

“…Nonetheless, examples of bismuth–thiophenecarboxylate complexes are known in the recent literature, though none of these reactions have been performed with bismuth nitrate, and as such, none of the resulting structures show the incorporation of the nitrate ion in the final products. In the literature, Bi V –TMC complexes are more prevalent;, however, only a single study utilizing this ligand scaffold with bismuth(III) exists. [10b] Moreover, certain considerations must first be regarded in comparing these two classes of compounds, not least of which is the alcohol solution and elevated temperatures needed to form the aforementioned organobismuth complexes; in contrast, aqueous conditions are employed in this study under ambient conditions.…”

“…Our interest in thiophene‐based ligand systems stems from their diverse biological properties, as well as their application in electronics and optoelectronics, medicine, and materials . Moreover, despite the limited number of reports examining Bi–thiophenecarboxylate complexes, the reported complexes have displayed unique structural chemistry, and in some instances, have been reported to exhibit anticancer activity . Herein, we demonstrate the utility of room‐temperature aqueous reactions in preparing these materials, and report the synthesis and characterization of five novel bismuth–carboxylate compounds that were isolated from reactions of bismuth precursors, 2‐thiophenemonocarboxylic acid, and pyridine in water.…”

“…Homo‐ and heterometallic bismuth‐based compounds have recently received significant interest due to their attractive materials properties and their promising application in areas such as biomedicine, catalysis, magnetism, data storage, and nonlinear optic and luminescent materials . Bismuth carboxylates, in particular, have been important compounds for chemotherapy and have more recently shown promise as photoactive materials . Yet in comparison with other main group elements, as well as those of the d‐ and f‐blocks, the structural chemistry of bismuth–carboxylate compounds is relatively unexplored.…”

Organic Compounds of Bismuth: Synthesis, Structure, and Applications

“…Another method for the synthesis of triarylbismuth dicarboxylates is based on the substitution of halogen atoms in triarylbismuth dihalides. Triphenylbismuth dicarboxylates Ph 3 Bi[OC(O)R] 2 (R = C 6 H 3 F 2 -3,5, C 6 H 4 CF 3 -4, and C 4 H 3 S) were synthesized via this scheme by mixing solutions of triphenylbismuth dichloride and sodium salt of the acid in methanol [162].…”

Three-phenyl transfer in palladium-catalyzed C C coupling reactions by triarylbismuths: A mechanistic study

“…Bismuth compounds 1 find widespread applications in medicine as gastrointestinal agents, 2,3 anticancer drugs, 4,5 and antibiotics. 6,7 In materials science, triphenylbismuth has proven to be an effective contrast medium, 8,9,10 and Bi(III) homobimetallic complexes have shown potential as molecular switches.…”