Synthesis, crystal structure and biological activity of thiophene-2-carboxaldehyde thiosemicarbazone and its tin complexes

Tin(IV) complexes of 2‐benzoylpyridine N(4)‐phenyl‐thiosemicarbazone: spectral characterization, structural studies and antifungal activity

“…28 The antifungal properties of tin complexes are well known, 29 and some studies report that tin(IV) complexes of thiosemicarbazones could be good candidates as antifungal agents. 30 In the present study, the activity of the thiosemicarbazone was lowered on coordination to tin, probably due to the bulkiness of the complexes, which do not facilitate their permeation through the yeast membrane. In complex 1, the presence of three chlorine atoms possibly leads to a more lipophilic compound, which could cross the cell membrane better than the other two complexes.…”

Synthesis, characterization, crystal structure and electrochemical behavior of a nickel(II) complex of 5,6-dihydro-2H-pyran-3-aldehyde thiosemicarbazone

“…Heterocyclic thiosemicarbazones and their metal complexes are among the most widely studied compounds for their potential therapeutic uses, such as antitumoral [1][2][3][4][5], antibacterial [6,7], and antifungal [8,9] activity, etc. The antitumor activity of thiosemicarbazones is enhanced by the presence of some metallic ions due to their ability to form chelates [10,11].…”

Crystal structure of N,N′-(1,6-hexamethylene)-bis(benzoylthiourea), C22H26N4O2S2

“…Thioureaand its derivatives, especially acylthiourea,are extensivelystudied because of their biologicalactivities such asherbicides, insecticides, plant-growth regulators,antifungaland pharmacodynamics [1][2][3][4]. Some thioureasare organic reaction catalyst in the metal-catalyzed asymmetric reduction of carbonyl compounds and carbonylativecyclization of o -hydroxyarylacetylenes [5,6].…”