Synthesis, complexation, spectral and antimicrobial study of some novel 5-bromo-2-fluorobenzaldehydeoxime and semicarbazone under ultrasonic irradiation

Emayavaramban, M.; Kumar, K. Yogesh; Mani, Periyar; Prabhakaran, Balakrishnan; Muthuvel, A.

doi:10.14419/ijac.v2i1.1628

Cited by 6 publications

(4 citation statements)

References 7 publications

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“…The mixed ligand complexes of [M (OAcPh-en) (Ben-opd)] H2O [M=Ni (II), Cu (II), Co (II), Mn(II) and Zn(II)] were also prepared similarly. The formation of the complexes may be represented by the following equations [10][11][12] OAcPh + en H2O OAcPh-en Ben + en H2O Ben-en…”

Section: Preparation Of the Complexesmentioning

confidence: 99%

Synthesis, designing, characterization and anti-microbial studies of N, N'- Bis (2 hydroxyacetophenone) Ethylenediamine metal (II) complexes

Nyah¹,

Ukpong²,

Okon³

et al. 2021

Global J. Eng. Tech. Adv.

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Tetra dentate Schiff base N, N’-bis [2-hydroxyacetophenone] ethylendiamine (OAcPh-en) were formed by the 2:1 molar condensation of 2-hydroxyacetophenone with ethylenediamine. Their Ni(II), Cu(II), Co(II), Mn(II), Fe(II) and Zn(II) diaquo complexes (I) were synthesized. The neutral bidentate ligand derived from benzaldehyde and ethylenediamine or o-phenylenediamine in 1:1 molar ratio in alcoholic solution yield bis[benzylidene] ethylenediamine (Ben-en) or bis [benzylidene] o-phenylinediamine (Ben-opd) (II). Further reaction between (I) and (II) in alcohol yielded mixed ligand complexes. The characterization of these newly synthesized mixed-ligand complexes were done by elemental analysis, magnetic measurements, infrared spectra and uv-visible spectra, thermo gravimetric analysis, anti-microbial studies have also been under taken

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Section: Preparation Of the Complexesmentioning

confidence: 99%

Synthesis, designing, characterization and anti-microbial studies of N, N'- Bis (2 hydroxyacetophenone) Ethylenediamine metal (II) complexes

Nyah¹,

Ukpong²,

Okon³

et al. 2021

Global J. Eng. Tech. Adv.

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“…The chemistry of Schiff base transition metal complexes has become highly attractive due to their wide pharmacokinetic profile providing a variety of compounds with different activities [11][12][13][14][15]. In recent years, the distinguish ligands containing sulfur atom such as thiosemicarbazones derivatives and their complexes with some of transition metal ions have a great attention in the field of medicinal chemistry according to their therapeutic importance, such as anti-bacterial, anti-fungal, anti-viral, anti-allergic, anti-tumor, anticancer, and anti-HIV activities [16][17][18][19][20][21][22][23][24][25][26][27][28]. Based on these vital items, herein we reported the synthesis and spectroscopic characterization of two new Schiff base complexes of 2-(2-hydroxy-3-methoxybenzylidene) hydrazinecarbothioamide derivatives ligands with manganese(II), copper(II), and zinc(II) metal ions.…”

Section: Introductionmentioning

confidence: 99%

Solvent free synthesis of hydrazine carbothioamide derivatives as a precursor in the preparation of new mononuclear Mn(II), Cu(II), and Zn(II) complexes: Spectroscopic characterizations

Al‐Hazmi¹,

Saad²,

Alosaimi³

et al. 2021

Bull. Chem. Soc. Eth.

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ABSTRACT. Over the last few years considerable attention has been devoted to the study of Schiff base complexes of metal(II) containing nitrogen, oxygen and sulfur donor ligands due to their diverse biological activities. Therefore, the Schiff base thiosemicarbazone derivatives of 2-(2-hydroxy-3-methoxybenzylidene) hydrazine carbothioamide (HL1) and 2-(4-bromo-2-hydroxy-3-methoxybenzylidene) hydrazine carbothioamide (HL2) were synthesized with solvent free technique using silica gel as material support for the reaction. The structures of the precursor’s organic products confirmed with their 1H, 13C NMR, IR and microanalysis data. Six new manganese(II), copper(II), and zinc(II) complexes of HL1 and HL2 2-(2-hydroxy-3-methoxybenzylidene) hydrazinecarbothioamide derivatives with the general formulation [ML1Cl] and [ML2Cl], where M = Mn2+, Cu2+, and Zn2+ were prepared and well discussed by using elemental analyses, magnetic moments, molar conductance, infrared and electronic spectral techniques. The assignments data of spectroscopic analysis confirm that the synthesized thiosemicarbazone Schiff bases of acts as a tridentate ligand as sulfur-oxygen-nitrogen donating atoms. The values of magnetic moments agreed with the data of electronic spectra which both suggested a four-coordination geometry of the synthesized complexes. KEY WORDS: Schiff base, Thiosemicarbazone, Manganese(II) complex, Copper(II) complex, Zinc(II) complex Bull. Chem. Soc. Ethiop. 2021, 35(2), 413-424. DOI: https://dx.doi.org/10.4314/bcse.v35i2.14

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“…Schiff base ligands of heterocyclic compounds and their transition metal complexes are of great interest as simple structural models of biological system due to the presence of hetero atoms such nitrogen, oxygen and sulphur groups [13]. Schiff bases have gained importance in medicinal and pharmaceutical fields due to a broad spectrum of biological activities like anti-inflammatory [16][17][18][19][20], analgesic [21][22][23], antimicrobial [24,25], anticonvulsant [26], antitubercular [27], anticancer [28,29], antioxidant [30], antihelmintic [31], and so forth. The wide ranges of applications of these compounds have continued to attract interest among inorganic chemists.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Activity of Mn Complexes Incorporating Schiff Bases: A Short Review

Uddin¹

2019

AJHC

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Antibiotic resistance has been growing at an anxious rate and as a result the activity of antibiotics against Gram-negative and Gram-positive bacteria has dropped dramatically day by day. Metal ions play many critical functions in humans. Deficiency of some metal ions can lead to disease like pernicious anemia, growth retardation, heart disease in infants etc. In this sense there is a strong need to synthesis new substances that not only have good spectrum of activity, but having new mechanisms of action. Inorganic compounds particularly Mn metal complexes have played an important role in the development of new metal based drugs. Over the past few years, there have been many reports on their applications in homogeneous and heterogeneous catalysis. The activity is usually increased by complexation therefore to understand the properties of both ligands and metal can lead to the synthesis of highly active compounds. The influence of certain metals on the biological activity of these compounds and their intrinsic chemical interest as multidentate ligands has prompted a considerable increase in the study of their coordination behavior. Development of a new chemotherapeutic Schiff bases and their metal complexes is now attracting the attention of medicinal chemists. In this review we have focused on research of Mn complexes incorporation of Schiff bases carry out over the past few decades which has sought to possess preclinical pharmacological screenings like anti-bacterial, anti-fungal, anti-tuberculosis, anti-inflammatory, anti-cancer, DNA-interaction and anti-tumor action of synthetic metal complexes.

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Synthesis, complexation, spectral and antimicrobial study of some novel 5-bromo-2-fluorobenzaldehydeoxime and semicarbazone under ultrasonic irradiation

Cited by 6 publications

References 7 publications

Synthesis, designing, characterization and anti-microbial studies of N, N'- Bis (2 hydroxyacetophenone) Ethylenediamine metal (II) complexes

Synthesis, designing, characterization and anti-microbial studies of N, N'- Bis (2 hydroxyacetophenone) Ethylenediamine metal (II) complexes

Solvent free synthesis of hydrazine carbothioamide derivatives as a precursor in the preparation of new mononuclear Mn(II), Cu(II), and Zn(II) complexes: Spectroscopic characterizations

Antimicrobial Activity of Mn Complexes Incorporating Schiff Bases: A Short Review

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