Synthesis, chemical characterization, DNA interaction and antioxidant studies of ortho, meta and para fluoro substituted ferrocene incorporated selenoureas

Solvent‐free Synthesis of Water‐Soluble New Pyridinium Amines: Spectroscopic Characterization, Biological Screening, and Interaction Study with DNA

“…2,2‐Diphenyl‐1‐picrylhydrazyl (DPPH) shows high absorbance at 517 nm. The color of the DPPH solution changes when an antioxidant is added to it, resulting in the decrease of absorbance . The antioxidant potential of 1–8 in terms of radical scavenging activity was checked via a spectrophotometric method using DPPH.…”

“…Figure shows the antioxidant potential of these compounds and their dose‐dependent behavior which is comparable to that of the standard. Compounds 2 and 3 exhibit remarkable activity due to the presence of the hydroxyl group …”

Synthesis, structural characterization, DNA binding and antioxidant potency of new ferrocene incorporated acyl ureas

“…In this struggle tremendous attention has been given to the ferrocene and its derivatives. Ferrocene [2], nitrophenyl ferrocene [3], antimony derivatives of ferrocene [1] and thiourea [4] and selenourea derivatives of ferrocene [5][6][7] have been evaluated for their interactions with DNA. It has been observed that almost all the derivatives of ferrocene have higher drug-DNA binding constant than simple positively charged ferrocene moiety (3.45 x 10 2 M -1 ) although when these derivatives are not coupled with ferrocene then they are themselves less active for DNA.…”

A new class of silica-supported chromo-fluorogenic chemosensors for anion recognition based on a selenourea scaffold

“…However, in this scenario, and, to the best of our knowledge, examples of selenourea-based anion sensors have never been reported in the literature to date despite selenoureas are interesting organoseleno compounds that show anticancer activity, antioxidant properties, enzyme inhibition, and DNA binding properties. [16][17][18][19][20] Taking these concepts into account and following our interest in anion recognition and sensing [21][22][23][24][25] we decided to explore the potential use of selenoureas as a new scaffold for the design of anion chemosensors.In particular, here, we describe the ability of the asymmetric 1-(4-methyl-2-oxo-2H-chromen-7-yl)-3-phenylselenourea (L) to act as a colorimetric and/or fluorescent sensor for S 2-and CNrecognition. L was obtained according to the reaction shown in Scheme 1.…”