Synthesis, characterization of some derivationes of 3-Nicotinc acide

Abstract

In This Research The Preparation Of Number heterocyclic compounds, Which include Seminars like compensators 1,3,4- oxadizole -2-thiol and AL Pyrazole -2- yl, Nicotinic Used as Vaw material in the Preparation .Attended ester During reactance nicotinic acid With thionyl Chloride in the presence of ethanol, The resultant ester were treated with hydrazine hydrate in ethanol the Corresponding hydrazide The synthesized hydrazides were converted to 1,3,4-oxadizoles by their reaction with carbon disulfide in potassium hydroxide, Use hydrazide To the praparation pyrazole during reactance with ethyl acetoacetate.