Abstract:Several new imidazole-5(4H)-one analog was synthesized using multi-step synthesis. All the synthesized compounds were characterized using FT-IR, 1H-NMR, Mass spectroscopy, and microanalysis to confirm their chemical structure. Molecular properties of the title compounds were predicted using Molinspiration online tool and binding studies of the title analogs against COX-1 & COX-2 were predicted by the molecular docking method. All novel imidazole-5(4H)-one analog were tested for their in-vivo anti-inflammat… Show more
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