Synthesis, characterization, crystal structure, and molecular docking of o-vanillin and l-valine derived molecules: a DFT study and antiproliferative activity against the PANC-1 cancer cell line

Abstract

Cu(II) complexes 1 & 2 with and without coligand (2,2’-bipyridyl) were synthesized using ligand NaLH=2-{(E)-[(2-hydroxy-3-methoxyphenyl)methylidene]amino}-3-methylbutanoic acid which is prepared from o-vanillin and L-valine. 1H-NMR, UV-Vis, FTIR techniques characterized the molecules while...