Synthesis, Characterization, Catalytic Activity, and DFT Calculations of Zn(II) Hydrazone Complexes

Adejumo, Temiloluwa T.; Tzouras, Nikolaos V.; Zorba, Leandros P.; Radanović, Dušanka; Pevec, Andrej; Grubišić, Sonja; Mitić, Dragana; Anđelković, Katarina; Vougioukalakis, Georgios C.; Čobeljić, Božidar; Turel, Iztok

doi:10.3390/molecules25184043

Cited by 60 publications

(32 citation statements)

References 58 publications

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“…These structures are called soft molecules. 34 In this study, ΔE values are listed as 9> 8> 7> 6. As a result, it can be said that molecule 6 can show good corrosion inhibitor performance (Table II).…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Theoretical calculation of newly synthesized tetrazolopyrimidine derivatives as a potential corrosion inhibitor

Ergan

Seker

Akbaş

et al. 2022

JSCS

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In this work, we wanted to define a general and comprehensive strategy for the synthesis of tetrazolo[1,5-a]pyrimidine derivatives. For this purpose, we obtained new tetrazolo[1,5-a]pyrimidine molecules via the mercury-promoted desulfurization reaction, including hydrolysis, cyclizations, and eliminations. All of the molecules were characterized by FT-IR, 1H NMR, 13C NMR, and elemental analysis. On the other hand, the potentials of compounds as corrosion inhibitors were calculated at B3LYP / 6-31G (d, p) level via density functional theory (DFT).

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Section: Accepted Manuscriptmentioning

confidence: 99%

Theoretical calculation of newly synthesized tetrazolopyrimidine derivatives as a potential corrosion inhibitor

Ergan

Seker

Akbaş

et al. 2022

JSCS

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“…Investigation of various arylnitrones (Scheme 6), concluded that either electron-withdrawing or electron-donating groups on various positions of the phenyl-imino moieties yielded the desired quinolines in high yields (67)(68)(69)(70)(71). Derivatives bearing groups of either electron-withdrawing or -donating ability at either the paraor the metaposition of the phenyl ring bearing the N-O group gave the corresponding products in approximately 80% yield (72)(73)(74)(75). Attempts with heterocyclicsubstituted nitrones failed, most probably owing to the strong metal-heteroatom coordination.…”

Section: Transformations With N-oxide As Tdgmentioning

confidence: 99%

“…All aforementioned aspects of sustainable transition metal-catalyzed C-H activation reactions constitute important weapons in the arsenal of contemporary organic chemistry. In this article, enabled by our ongoing interest in the area of sustainable catalysis [40,[68][69][70][71][72][73][74][75][76], we review and critically examine the use of traceless directing groups (TDG) in sustainable metal catalyzed C-H activation, highlighting the versatility provided by these categories of DGs coupled with earth-abundant, sustainable metals. In line with our previous work [40], we examine the advancements regarding the use of TDGs in transformations catalyzed by complexes of the most abundant, least toxic and biocompatible 3d metals.…”

Section: Introductionmentioning

confidence: 99%

Traceless Directing Groups in Sustainable Metal-Catalyzed C–H Activation

et al. 2021

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Sustainable transformations towards the production of valuable chemicals constantly attract interest, both in terms of academic and applied research. C–H activation has long been scrutinized in this regard, given that it offers a straightforward pathway to prepare compounds of great significance. In this context, directing groups (DG) have paved the way for chemical transformations that had not been achievable using traditional reactions. Few steps, high yields, selectivity and activation of inert substrates are some of the invaluable assets of directed catalysis. Additionally, the employment of traceless directing groups (TDG) greatly improves and simplifies this strategy, enabling the realization of multi-step reactions in one-pot, cascade procedures. Cheap, abundant, readily available transition metal salts and complexes can catalyze a plethora of reactions employing TDGs, usually under low catalyst loadings—rarely under stoichiometric amounts, leading in greater atom economy and milder conditions with increased yields and step-economy. This review article summarizes all the work done on TDG-assisted catalysis with manganese, iron, cobalt, nickel, or copper catalysts, and discusses the structure-activity relationships observed, by presenting the catalytic pathways and range of transformations reported thus far.

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“…A class of heterocyclic azo dyes is the thiazolylazo dye. Thiazoles are an important class of heterocyclic compounds which are related with many types of biological properties, probably by virtue of the -N=C-S− group, these include insecticidal, herbicidal, anti-oxidant, -bacterial, -convulsant and -inflammatory [29] [30] [31] [32] [33]. Thiazoles are readily capable of crossing cellular membranes owing to their better liposolubility, attributed to the presence of a sulphur atom [32].…”

Section: Introductionmentioning

confidence: 99%

Syntheses, Characterization and Biological Activity of Novel Thiazoylazo Dye and Its Coordination Compounds

Aiyelabola¹

2021

ABC

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The present work describes the synthesis of a novel heterocyclic azo dye by general diazonization of 2-amino-4,5-dimethylthiazole followed by the diazocoupling of the resulting diazonium ion with 5-methyl-2-(propan-2-yl)phenol to obtain ligand L. This was characterized using Fourier-transformed infrared and electronic spectrophotometry. Ligand L was further coordinated with five metal ions, M:L, 1:2 [M = Cu(II), Mn(II), Zn(II), Ni(II) and Co(II)]. The coordination compounds obtained were characterized by electronic, IR spectrophotometry, magnetic susceptibility and percentage metal analyses. The results obtained suggested that a thiazoylazo dye was obtained as ligand L. It was proposed that two molecules of the solvent coordinated to the metal ion in addition with the ligands to give an octahedral geometry for copper(II), manganese(II) and nickel(II) complexes. On the other hand, square planar geometry was suggested for zinc(II) and cobalt(II) complexes. The anti-inflammatory activity of the ligand and coordination compounds was evaluated using four in vitro-based assays viz: xanthine oxidase and lipoxygenase inhibition assay, membrane stability and protein denaturation assay. The synthesized compounds generally exhibited good anti-inflammatory activity in all the assays carried out. However, the reference standards, in this instance, were more effective in the case of xanthine oxidase, lipoxygenase and protein denaturation inhibitory assays. For the membrane stability study, the coordination compounds and ligand L elicited more potent anti-inflammatory activity than the standard drug.

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Synthesis, Characterization, Catalytic Activity, and DFT Calculations of Zn(II) Hydrazone Complexes

Cited by 60 publications

References 58 publications

Theoretical calculation of newly synthesized tetrazolopyrimidine derivatives as a potential corrosion inhibitor

Theoretical calculation of newly synthesized tetrazolopyrimidine derivatives as a potential corrosion inhibitor

Traceless Directing Groups in Sustainable Metal-Catalyzed C–H Activation

Syntheses, Characterization and Biological Activity of Novel Thiazoylazo Dye and Its Coordination Compounds

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