Synthesis, characterization and X-ray structures of bis(arytelluro)ethynes

Farran, Joan; Torres-Castellanos, Libardo; Álvarez‐Larena, Ángel; Piniella, J. F.; Capparelli, Mario V.

doi:10.1016/s0022-328x(02)01381-5

Cited by 9 publications

(4 citation statements)

References 63 publications

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“…Within our program of synthetic and structural studies of organotellurium compounds [4], we prepared the title compound and determined its crystal structure. The asymmetric unit con- …”

Section: Discussionmentioning

confidence: 99%

Crystal structure of bis(4-dimethylaminophenyl)telluride, (4-Me2NC6H4)2Te

J.¹,

Torres-Castellanos²,

Alvarez-Larena³

et al. 2002

Zeitschrift Für Kristallographie - New Crystal Structures

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“…Within our program of synthetic and structural studies of organotellurium compounds [4], we prepared the title compound and determined its crystal structure. The asymmetric unit con- …”

Section: Discussionmentioning

confidence: 99%

Crystal structure of bis(4-dimethylaminophenyl)telluride, (4-Me2NC6H4)2Te

J.¹,

Torres-Castellanos²,

Alvarez-Larena³

et al. 2002

Zeitschrift Für Kristallographie - New Crystal Structures

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“…Finally, four of the structures have linear topologies with a single example of a zig-zag topology, Table 12.3. There is a sole example of Te(lone pair)···π(aryl) interactions leading to a threedimensional architecture, that is, 39 [54], Scheme 12.6. Both tellurium atoms in this [42] 3.55 9.3 linear 25 [43] 3.62 6.9 helical 26 [44] 3.66 10.2 helical 27 [45] 3.71 13.1 helical 28 [46] 3.72 8.5 zig-zag 29 [47] 3.82 14.7 helical 30 [48] 3.86 12.2 helical 31 [49] 3.88 9.1 zig-zag 32 [48] 3.89 11.2 zig-zag 33 [38] 3 …”

Section: Scheme 123 (Continued)mentioning

confidence: 98%

“…With the exception of one structure, the remaining tellurium structures featuring Te(lone pair)···π (aryl) synthons, that is, 23-38 [38,[41][42][43][44][45][46][47][48][49][50][51][52][53] adopt one-dimensional aggregation patterns in their crystal structures, see Table 12.3 for data. There are basically two variations in that the majority, 11 examples, that is, 23-33, have the chains sustained by single Te(lone pair) ··π (aryl) interactions, whereas there are five examples whereby the chains are sustained by two Te(lone pair) .…”

Section: Scheme 123 (Continued)mentioning

confidence: 99%

Supramolecular Aggregation Patterns and Stereochemical Consequences of Tellurium(Lone Pair)…π(Aryl) Interactions

Haiduc

Tiekink

Zukerman-Schpector

2012

The Importance of Pi‐Interactions in Crystal Engineering

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While the formation of π-aryl bonds is typical for transition metals, the main-group elements display a reduced tendency to form π -aryl complexes. This being stated, it was established by the report of the so-called "Menschutkin's complexes", for example, C 6 H 6 .SbCl 3 [1], that main-group element compounds can and do form such interactions. In the case of transition-metal systems, metal···π interactions are readily rationalised in terms of electron donation from the electron-rich aryl system to the electropositive metal centre. By contrast, allied interactions with main-group elements, often having a lone pair of electrons, seems counterintuitive. However, as indicated from macromolecular chemistry [2,3], heteroatom(lone pair)···π (aryl) interactions are stabilising. Theoretical studies indicate energies of stabilisation ranging from 1.5 to 5.1 kJ mol −1 [4,5]. The heteroatom(lone

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“…In line with this, an infinite number of neurotoxicants can modify the activity of Ca 2+ -handling proteins, including the Ca 2+ pumps and channels [21][22][23][24]. In addition to their important role as synthetic intermediaries in organic synthesis [25][26][27][28][29], which increase the risk of occupational exposure to chalcogenides, organic forms of selenium and tellurium have been pointed out by several investigators as potential pharmacological therapeutic agents. It has been suggested that utilization of the redox activity of the selenium and tellurium atoms of such compounds provides antioxidants of considerable potency, suitable as tools in free-radical biology and medicine [30][31][32][33][34][35][36][37].…”

Section: Camentioning

confidence: 99%

Voltage‐dependent ebselen and diorganochalcogenides inhibition of ⁴⁵Ca²⁺ influx into brain synaptosomes

Moretto

Rossato

Nogueira

et al. 2003

J Biochem & Molecular Tox

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By mediating the Ca(2+) influx, Ca(2+) channels play a central role in neurotransmission. Chemical agents that potentially interfere with Ca(2+) homeostasis are potential toxic agents. In the present investigation, changes in Ca(2+) influx into synaptosomes by organic forms of selenium and tellurium were examined under nondepolarizing and depolarizing conditions induced by high KCl concentration (135 mM) or by 4-aminopyridine (4-AP). Under nondepolarizing conditions, ebselen (400 micro M) increased Ca(2+) influx; diphenyl ditelluride (40-400 micro M) decreased Ca(2+) in all concentrations tested; and diphenyl diselenide decreased Ca(2+) influx at 40 and 100 micro M, but had no effect at 400 micro M. In the presence of KCl as depolarizing agent, ebselen and diphenyl ditelluride decreased Ca(2+) influx in a linear fashion. In contrast, diphenyl diselenide did not modify Ca(2+) influx into isolated nerve terminals. In the presence of 4-AP (3 mM) as depolarizing agent, ebselen (400 micro M) caused a significant increase, whereas diphenyl diselenide and diphenyl ditelluride inhibited Ca(2+) influx into synaptosomes. The results can be explained by the fact that the mechanism through which 4-AP and high K(+) induced elevation of intracellular Ca(2+) is not exactly coincident. The mechanism by which diphenyl ditelluride and ebselen interact with Ca(2+) channel is unknown, but may be related to reactivity with critical sulfhydryl groups in the protein complex. The results of the present study indicate that the effects of organochalcogenides were rather complex depending on the condition and the depolarizing agent used.

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Synthesis, characterization and X-ray structures of bis(arytelluro)ethynes

Cited by 9 publications

References 63 publications

Crystal structure of bis(4-dimethylaminophenyl)telluride, (4-Me2NC6H4)2Te

Crystal structure of bis(4-dimethylaminophenyl)telluride, (4-Me2NC6H4)2Te

Supramolecular Aggregation Patterns and Stereochemical Consequences of Tellurium(Lone Pair)…π(Aryl) Interactions

Voltage‐dependent ebselen and diorganochalcogenides inhibition of ⁴⁵Ca²⁺ influx into brain synaptosomes

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Synthesis, characterization and X-ray structures of bis(arytelluro)ethynes

Cited by 9 publications

References 63 publications

Crystal structure of bis(4-dimethylaminophenyl)telluride, (4-Me2NC6H4)2Te

Crystal structure of bis(4-dimethylaminophenyl)telluride, (4-Me2NC6H4)2Te

Supramolecular Aggregation Patterns and Stereochemical Consequences of Tellurium(Lone Pair)…π(Aryl) Interactions

Voltage‐dependent ebselen and diorganochalcogenides inhibition of 45Ca2+ influx into brain synaptosomes

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Voltage‐dependent ebselen and diorganochalcogenides inhibition of ⁴⁵Ca²⁺ influx into brain synaptosomes