Synthesis, Characterization and Spectral Studies of Gold Complex with Gliclazide, An Oral Antidiabetic Allopathic Drug

Abstract

Synthesis, characterization and spectral studies of gold complex with gliclazide, an oral antidiabetic drug have been studied. The conductometric titration using monovariation method indicate that complexes are non-ionic and L 2 M type. Analytical data agrees with the molecular formula(C 15 H 20 N 3 O 3 S) 2 Au. Structure of complex was assigned tetrahedral, supported by IR, 1 H-NMR.X-Ray and Mass studies. Structure (II) is proposed for complex.

Growth and Characterization of Urea L-valine a Organic Non Linear Optical Crystals

“…The powder XRD result of this crystal was compared with previous reports in which urea and L-valine were mixed with acids and metals. From the XRD peak intensity it is concluded that in the present work crystalline nature was very high while comparing previous reports [10][11][12][13][14][15] .…”

FTIR, UV-Vis, magnetic, mass spectral and XRD studies of Ni(II) complex with pioglitazone: An oral antidiabetic drug

“…From the crystallographic data [21][22][23][24][25][26] unit cell parameters are obtained for Ni complex which attributed to orthorhombic crystal system. The particle size of pioglitazone-nickle complex is 19.871 microns respectively, which is calculated from X-ray line broadening using the Scherrer formula;…”

Synthesis, Characterization and Biological Evaluation of Transition and Inner Transition Metal Complexes of Ligands Derived Schiff Base from 1-phenyl-2, 3-dimethyl-4-(4-iminopentan-2-one)-pyrazole-5-one and 2-aminophenol

“…The molar conductance was measured with digital conductivity meter (HPG system G-3001) using a Digital conductivity bridge in DMF and DMSO at 10 -3 M dilution at room temperature. Magnetic susceptibility was determined by Gouy's balance [13] using CuSO 4 .5H 2 O as calibrant. The electronic spectra of the complexes were recorded by Beckmann-DU-Spectrophotometer (Fullerton, California 92834-3100, USA).…”

“…It is known that the existence of metal ions bonded to biologically active compounds may increase their activities [11][12][13][14] . In recent years, because of new interesting applications found in the field of medicine, the metal complexes with tridentate O, N, N types of alternative structures have attracted the attention of chemist.…”