Synthesis, characterization, and photocatalytic activity of Co(II) and Cu(II) phthalocyanines linked with thiophene–Schiff base substituents for 4-nitrophenol oxidation

Kamiloğlu, Ayşe Aktaş; Saka, Ece Tuğba; Acar, İrfan; Tekintas, Kader

doi:10.1080/00958972.2019.1657101

Cited by 7 publications

(3 citation statements)

References 66 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The OH signal disappeared in compound (a)'s 1 H-NMR spectra at δ = 5.0 ppm (Figure 1). Compound (a) exhibited a nitrile carbon atom (C ≡ N) at δ = 115.90 and 115.37 ppm, according to its 13 C-NMR spectra. The molecular ion peak in the mass spectra of phthalonitrile compound (a) was found at m/z: 319.78 [M] + , confirming the suggested chemical structure (Figure 2).…”

Section: Characterizations Of All Synthesized Compoundsmentioning

confidence: 99%

“…Phthalocyanine complexes (Pcs) are used in many application areas because of their many unique properties 5 . These are solar cells, 6 electrochemistry, 7 photodynamic therapy (PDT), 8,9 antimicrobial agents, 10 electrocatalytic, 11 photocatalytic, 12–14 anti‐cancer, 15 and antioxidant 16 . The chemical properties of the side groups in substituted phthalocyanines significantly influence the properties of Pcs, such as electronic absorption, solubility, aggregation, and usability in application areas 17 .…”

Section: Introductionmentioning

confidence: 99%

“…The synthesis route of compounds (a and 1-6). (i) K 2 CO 3 , dry DMF, 60 C, N 2(g) ; (ii) n-pentanol, DBU, CoCl 2 , CuCl 2 , Zn (OAc) 2 , N 2(g) , 140 C; (iii) reflux temperature, THF, N 2(g) .F I G U R E 1 1 H (a) and13 C (b) NMR spectra of phthalonitrile compound (a).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Synthesis and in vitro acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes activity of aldehyde and Schiff base substituted cobalt (II), copper (II), and zinc (II) phthalocyanines

Yalazan,

Kamiloglu,

Tekin

et al. 2024

Applied Organom Chemis

View full text Add to dashboard Cite

In this work, a series of aldehyde‐substituted phthalocyanine compounds (1, 3, and 5) were prepared by the cyclotetramerization of the 4‐(5‐(diethylamino)‐2‐formylphenoxy) phthalonitrile (a) and the corresponding metal salts. Schiff base‐substituted phthalocyanines (2, 4, and 6) were derived from an aldehyde‐substituted phthalocyanine (1, 3, and 5) via the reaction of aldehyde‐substituted phthalocyanines with an amine reagent. The compounds that were obtained were characterized using FT‐IR, 1H {13C} NMR, UV–Vis, and MS spectra (a and 1–6). The inhibitory qualities of synthesized aldehyde and Schiff base‐substituted complexes against the enzymes butyrylcholinesterase (BChE) and acetylcholinesterase (AChE) were assessed. The majority of phthalocyanines exhibited strong enzyme‐inhibiting properties. Out of the six produced phthalocyanines, 3 and 4 displayed the most intriguing profiles as submicromolar selective AChE inhibitors (IC50 = 0.060 μM), whereas 1 demonstrated the most potent BChE inhibitor (IC50 = 0.024 μM). The aggregation studies of CoPcs, CuPcs, and ZnPcs (1–6) were also carried out in this work.

show abstract

Section: Characterizations Of All Synthesized Compoundsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Synthesis and in vitro acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes activity of aldehyde and Schiff base substituted cobalt (II), copper (II), and zinc (II) phthalocyanines

Yalazan,

Kamiloglu,

Tekin

et al. 2024

Applied Organom Chemis

View full text Add to dashboard Cite

show abstract

Chlorine‐Thymol Substituted Silicon (IV) Phthalocyanines: Synthesis, Characterization, and In Vitro Acetylcholinesterase (AChE)/Butyrylcholinesterase (BChE) Inhibitory Effect

Aktas Kamiloglu,

Arslan,

Tekin

et al. 2024

Applied Organom Chemis

View full text Add to dashboard Cite

In this study, novel chlorine‐thymol derivatives (1,3‐bis(4‐chloro‐2‐isopropyl‐5 methylphenoxy)propan‐2‐ol (Thy‐OHI) and 2‐[2‐(4‐chloro‐2‐isopropyl‐5‐methylphenoxy)ethoxy]ethanol (Thy‐OHII)) and axially di‐4‐chloro‐2‐isopropyl‐5‐methylphenoxy (Thy‐SiPc), 1,3‐bis(4‐chloro‐2‐isopropyl‐5‐methylphenoxy)propanoxy (Thy‐OHI‐SiPc), and 2‐[2‐(4‐chloro‐2‐isopropyl‐5‐methylphenoxy)ethoxy]ethanoxy (Thy‐OHII‐SiPc) substituted silicon phthalocyanine compounds were obtained, and their structures were elucidated by the combination of various methods such as NMR, IR, UV–Vis, and MS. The inhibitory effects of these compounds (Thy‐OHI, Thy‐OHII, Thy‐SiPc, Thy‐OHI‐SiPc and Thy‐OHII‐SiPc), synthesized for the first time, on cholinesterase enzymes (AChE and BChE) were investigated in the laboratory environment. In the studies, notably Thy‐OHI‐Si and thymol derivative ligand Thy‐OHII displayed significant inhibition against AChE and BChE.

show abstract

Design, syntheses, spectroscopic, aggregation properties of novel peripheral octa-substituted zinc(II), magnesium(II) and lead(II) phthalocyanines and investigation of their photocatalytic properties on the photooxidation of 4-nitrophenol

Yalazan

Tekintas

Serdaroğlu

et al. 2020

Inorganic Chemistry Communications

View full text Add to dashboard Cite

Synthesis, characterization, and photocatalytic activity of Co(II) and Cu(II) phthalocyanines linked with thiophene–Schiff base substituents for 4-nitrophenol oxidation

Cited by 7 publications

References 66 publications

Synthesis and in vitro acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes activity of aldehyde and Schiff base substituted cobalt (II), copper (II), and zinc (II) phthalocyanines

Synthesis and in vitro acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes activity of aldehyde and Schiff base substituted cobalt (II), copper (II), and zinc (II) phthalocyanines

Chlorine‐Thymol Substituted Silicon (IV) Phthalocyanines: Synthesis, Characterization, and In Vitro Acetylcholinesterase (AChE)/Butyrylcholinesterase (BChE) Inhibitory Effect

Design, syntheses, spectroscopic, aggregation properties of novel peripheral octa-substituted zinc(II), magnesium(II) and lead(II) phthalocyanines and investigation of their photocatalytic properties on the photooxidation of 4-nitrophenol

Contact Info

Product

Resources

About