Synthesis, characterization and interaction with bovine serum albumin of cyclometallated Pd(II) complexes containing arylimine and salicylaldimine co-ligands

Jin, Xudong; Yang, Yichun; Jiang, Yuchun; Han, Xiao; Wan, Xiaowen; Liu, Daliang; Song, Xi‐Ming; Chang, Xiaohong

doi:10.1016/j.jorganchem.2015.04.050

Cited by 9 publications

(2 citation statements)

References 37 publications

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“…The procedure was repeated for a blank solution containing 1.0 mL of reagent solution. The TAC studies were performed three times and the mean was expressed as equivalents of ascorbic acid [22] 13 The 1 H NMR spectra of the salicylaldimines displayed a singlet signal at δ 13.90-12.70 ppm which was attributed to the phenolic -OH protons [18,27,[29][30][31][32][33]. All the salicylaldimines displayed a singlet signal at δ 8.91-8.85 ppm assigned to the azomethine (−HC=N) protons [15,27,30,31,[33][34][35][36] which further confirmed the formation of the salicylaldimines.…”

Section: Phosphomolybdate Total Antioxidant Capacity Assaymentioning

confidence: 99%

DFT Calculations and Total Antioxidant Capacity Studies of some Substituted Monodentate Salicylaldimines

Demehin¹

2021

JSRR

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Three substituted monodentate salicylaldimines namely 5-chloro-N-[(2- methoxy) phenyl] salicylaldimine [I], 5-chloro-N-[(4-chloro)phenyl]salicylaldimine [II] and 5-chloro-N-[(2-methyl-5-chloro)phenyl] salicylaldimine [III] were synthesized and characterized by elemental analysis, IR, UV, 1H and 13C NMR. Theoretical calculations were also performed on the optimized structures of the compounds. The IR, NMR and UV spectra of the compounds were calculated and the results compared with the corresponding experimental spectra to augment the structural elucidation. The calculated IR, NMR and UV values were in agreement with the experimental results. The total antioxidant capacities of the compounds were determined by phosphomolybdenum assay.

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Section: Phosphomolybdate Total Antioxidant Capacity Assaymentioning

confidence: 99%

DFT Calculations and Total Antioxidant Capacity Studies of some Substituted Monodentate Salicylaldimines

Demehin¹

2021

JSRR

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“…A proteína albumina sérica bovina (BSA) é amplamente utilizada como modelo em estudos de interação devido às suas semelhanças com a albumina sérica humana (HSA) [89]. As albuminas séricas atuam no organismo como transportadoras de substâncias exógenas e endógenas e estão presentes em altas concentrações no plasma sanguíneo [71]. Os resíduos de aminoácidos responsáveis pela fluorescência da proteína BSA são triptofano, tirosina e fenilalanina [90] e a supressão da fluorescência desses fluoróforos ocorre quando há interações moleculares através de processos como rearranjos moleculares, transferência de energia, formação de complexos e supressão por colisões [90].…”

Section: Estudo De Interação Com Bsa Por Espectroscopia De Fluorescênciaunclassified

Complexos metálicos de Ag(I) e Pt(II) com aminoadamantanos

Karla dos Santos Pereira

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Salicylaldimine‐bridged dinuclear cyclopalladated complexes: Synthesis, characterization and BSA binding studies

Gao

Zhang

et al. 2019

Applied Organom Chemis

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Salicylaldimine‐bridged dinuclear cyclopalladated complexes were synthesized by the reactions of cyclopalladated chloro dimers [Pd{(4‐R)C6H3CH=N‐C6H3–2,6‐i‐Pr2}(μ‐Cl)]2 (R = H; OMe) with salen‐based bridging ligands. The complexes were characterized by FTIR, NMR spectroscopy, elemental analysis and X‐ray crystallography. The binding interaction of cyclopalladated complexes to bovine serum albumin (BSA) was investigated by UV–vis, fluorescence and synchronous fluorescence spectroscopy. The experimental results showed that these Pd (II) complexes could bind to BSA with high affinity and quench its intrinsic fluorescence by a static or combined process. Also the interaction of Pd complexes with BSA affected the conformation of the tryptophan and tyrosine residues.

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Synthesis, characterization and interaction with bovine serum albumin of cyclometallated Pd(II) complexes containing arylimine and salicylaldimine co-ligands

Cited by 9 publications

References 37 publications

DFT Calculations and Total Antioxidant Capacity Studies of some Substituted Monodentate Salicylaldimines

DFT Calculations and Total Antioxidant Capacity Studies of some Substituted Monodentate Salicylaldimines

Complexos metálicos de Ag(I) e Pt(II) com aminoadamantanos

Salicylaldimine‐bridged dinuclear cyclopalladated complexes: Synthesis, characterization and BSA binding studies

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