Synthesis, characterization, and in vitro evaluation and in silico molecular docking of thiourea derivatives incorporating 4-(trifluoromethyl)phenyl moiety

Synthesis, Crystal Structure, Biological Evaluation and in Silico Studies on Novel (E)‐1‐(Substituted Benzylidene)‐4‐(3‐isopropylphenyl)thiosemicarbazone Derivatives

“…The medium intensity bands emerged at 733–692 cm −1 were arranged the C=S stretching vibrations in the FT‐IR spectra and accorded with FT‐IR characteristics of C=S bond (800–600 cm −1 ) [27] . The C−F stretching vibrations on the phenyl group were ascribed to 1120–1100 cm −1 in the FT‐IR spectra, which was close to the reported values (1114–1103 cm −1 ) [28] . The bands observed at 925, 860, 842 and 805 cm −1 in the FT‐IR spectra of compounds 1 – 8 were dealt with twisting vibrations of C−H, while the bands located at 590, 561 and 458 cm −1 were assigned to twisting vibrations of C−N [29] .…”

Synthesis, characterization, and the antifungal activity of chitosan derivatives containing urea groups

“…The spectra of urea groups presenting peaks at around 6.8-8.3 ppm associate with the protons on pyridine ring and benzene ring [21,27]. And the peaks at 8.39 ppm and 8.56 ppm should be related to the protons on NH in the molecules of urea groups [39,40]. Based on the above analyses, it is enough to confirm that the chitosan derivatives were obtained.…”

Synthesis, Characterization, Biological and Antitumor Activity of Co(II) , Ni (II) , Cu(II) and Zn (II) Complexes of N-(2-Chlorophenyl)-N’-Benzoyl Thiourea

“…These finding could be explained by the solubility effect as good relationship could be seen between activity and solubility of compounds. The activity of the complex could be explained by its greater solubility and lipophilicity increase with increasing bulkiness and may be facilitate transport through the cellular membrane [28].…”