Synthesis, characterization, and electrochemical study of a new tetradentate nickel(II)-Schiff base complex derived from ethylenediamine and 5′-(N-methyl-N-phenylaminomethyl)-2′-hydroxyacetophenone

Synthesis and In Vitro Pharmacological Evaluation of 5‐(Alkoxymethyl)‐2‐(3‐alkylamino‐2‐hydroxypropoxy)phenylethanones Related to Acebutolol and Celiprolol

“…The compounds were prepared by a four‐step synthesis using 2‐hydroxyphenylethanone as the starting material (Scheme ). In the first step (i), the chloromethyl derivative ( 1 ) was prepared by the reaction of the starting ketone with concentrated HCl and paraformaldehyde according to the published procedure . In the second step (ii), alkoxymethylderivatives ( 2a–h ) were obtained by reaction of the chloromethyl intermediate with the appropriate alcohol in the presence of NaHCO 3 .…”

Synthesis and characterizations of NiO nanoparticles via solid-state thermal decomposition of nickel(II) Schiff base complexes

“…Recently, nickel(II) Schiff base complexes have been widely investigated not only for their interesting structures and properties [1,2], but also for their use as precursor for preparation of nickel oxide nanoparticles [3]. Then, considerable interest has been grown on the preparation and characterization of NiO nanoparticles via thermal decomposition of complexes for their unique applications and properties [4,5]. Among the transition metal oxides, nickel oxide has attracted much attention due to its properties and applications [6,7].…”

Synthesis, Characterization and Nanochemistry of Novel Antibacterial Copper (II) Semicarbazone Complexes

“…Finally, anodic current after E pa decreases as the concentration of the copper (II) increases and thus redox cycle was completed. A new oxidation state is generated during forward scan and then comes back to original oxidation state in the reverse scan ,,. The values for reduction peak (E pc ), oxidation peak (E pa ) as well as anodic and cathodic peak currents (I pa and I pc ) are obtained from respective voltammograms and listed in Table .…”

“…Once inside the cell, the complexes dissociate into Cu (II) ions and semicarbazones. Organic semicarbazones assimilate within the cytoplasmic environment of the bacteria whereas the inorganic Cu (II) moieties are known to stimulate oxidative stress via generation of reactive oxygen species (ROS) in the bacterial cells that arrests DNA and respiratory sequence thereby resulting into cell lysis (Figure ) . Owing to multiple inhibitory mechanisms, Cu (II) complexes of semicarbazone derivatives are highly active even at low concentrations than the cyclic aliphatic semicarbazone derivatives.…”