Synthesis, Characterization and Biological Properties of Anions of Bivalent Transition Metal [Co(II) and Ni(II)] Complexes With Acylhydrazine Derived ONO Donor Schiff Bases

Chohan, Zahid H.; Farooq, Mehrin; Iqbal, Mazhar

doi:10.1155/mbd.2000.133

Cited by 22 publications

(21 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The metal complexes (1) and (3) significantly showed 100% inhibition against bacterial species (a) and (b), respectively. It is known that chelation tends to make the ligands act as more powerful and potent bactericidal agents, thus killing more of the bacteria than the parent Schiff bases do 34,35 . A possible explanation for this increased activity upon chelation is proposed here: it was suggested 33 that in the chelated complex, the positive charge of the metal is partially shared with the donor atoms present in the ligands and there is a p-electron delocalization over the whole chelate ring.…”

Section: Antibacterial Studiesmentioning

confidence: 99%

Antibacterial Schiff Bases of Oxalyl-hydrazine/diamide Incorporating Pyrrolyl and Salicylyl Moieties and of Their Zinc(II) Complexes

Chohan

Farooq

Scozzafava

et al. 2002

Journal of Enzyme Inhibition and Medicinal Chemistry

Self Cite

View full text Add to dashboard Cite

Schiff bases derived from oxaldiamide/oxalylhydrazine and pyrrol-2-carbaldehyde, or salicylaldehyde respectively, as well as their Zn(II) complexes have been prepared and tested as antibacterial agents. These Schiff bases function as tetradentate ligands, forming octahedral Zn(II) complexes. The ketonic form for the diamide derived Schiff base and the enolic form of the hydrazide derived Schiff base were the preferred tautomers for coordination of the metal ions. The title compounds and their Zn(II) derivatives were evaluated for antibacterial activity against several bacterial strains which easily develop resistance to classical antibiotics, such as Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. Some of them showed promising biological activity in inhibiting the growth of such organisms.

show abstract

Section: Antibacterial Studiesmentioning

confidence: 99%

Antibacterial Schiff Bases of Oxalyl-hydrazine/diamide Incorporating Pyrrolyl and Salicylyl Moieties and of Their Zinc(II) Complexes

Chohan

Farooq

Scozzafava

et al. 2002

Journal of Enzyme Inhibition and Medicinal Chemistry

Self Cite

View full text Add to dashboard Cite

show abstract

“…The increase in activity [21] is due to formation of a chelate. It is suggested [22] that, in the chelate, the positive charge of the metal is partially shared with the donor atoms of the ligands and there is p-electron delocalization over the whole chelate ring. This, in turn, increases the lipophilic character of the metal and favor its permeation through the lipoid layers of the bacterial membrane.…”

Section: Screening Of Compounds For Their Antimicrobial Activitymentioning

confidence: 99%

Poly[(2-Hydroxy-4-Methoxy Benzophenone) Butylene] Resin and its Polychelates with Lanthanides(III): Synthesis and Characterization

Patel

Joshi

2006

International Journal of Polymeric Materials

View full text Add to dashboard Cite

The resin (polymeric ligand) was prepared from 2-hydroxy-4-methoxy benzophenone with 1,4-butane diol in the presence of polyphosphoric acid as a catalyst at 160 C for 9 h. The poly[(2-hydroxy-4-methoxy benzophenone) butylene] L ¼ H(HMBP-BD) form 1:2, ML 2 , complexes with M ¼ La(III), Pr(III), Nd(III), Sm(III), Gd(III), Tb(III), and Dy(III). The polymeric ligand and its polychelates were characterized by elemental analyses, electronic spectra, and magnetic susceptibilities, IR-spectroscopy, NMR, and thermogravimetric analyses. The number average molecular weight (Mn) of the resin was determined by Vapour Pressure Osmometry (VPO). All the polychelates are paramagnetic in nature. The resins and their polychelates were screened for their antimicrobial activity against E. coli, B. substilis, S. aureus (bacteria), and S. cerevisiae (yeast). It was found that the polychelates show good antimicrobial activity compared to the free polymeric ligand.

show abstract

“…It is quite interesting to know that hydrazides exhibit keto‐enol tautomerism upon photoexcitation . Tautomerism in hydrazides is characterized by translocation of a proton from a donor (N―H) moiety to an acceptor moiety (C═O) with a pre‐established intramolecular hydrogen bond giving birth to a phototautomer phenomenon, commonly termed as excited state intramolecular proton transfer (ESIPT).…”

Section: Introductionmentioning

confidence: 99%

Exploring the possibilities of double proton transfer in hydrazides: A theoretical approach

Mohan

Satyanarayan

Trivedi

2019

J of Physical Organic Chem

View full text Add to dashboard Cite

Hydrazides are known to exhibit keto‐enol tautomerism upon photoexcitation. Theoretical aspects uncovering excited state intramolecular proton transfer (ESIPT) of N‐acylsubstituted hydrazides with bithiophene core have been investigated. Geometrical aspects of the system are expected to undergo double proton translocation at its excited state. However, potential energy surface study for all the molecules reveals an impossible concurrent double proton translocation and to a greater extent dubious step‐wise double proton translocation in the system. Potential energy scans reveal molecules possessing a lower forward barrier at its excited state in comparison with their ground state suggestive of possible excited state single proton transfer. Geometrical attributes and spectral analysis suggest the strengthening of intramolecular hydrogen bond (N―H▪▪▪O) at its excited state, favoring single proton translocation. Theoretical estimation of electronic energy transition for all the conformers yields good correlation with the experimental figures with an energy overestimation <0.17 eV.

show abstract

Synthesis, Characterization and Biological Properties of Anions of Bivalent Transition Metal [Co(II) and Ni(II)] Complexes With Acylhydrazine Derived ONO Donor Schiff Bases

Cited by 22 publications

References 4 publications

Antibacterial Schiff Bases of Oxalyl-hydrazine/diamide Incorporating Pyrrolyl and Salicylyl Moieties and of Their Zinc(II) Complexes

Antibacterial Schiff Bases of Oxalyl-hydrazine/diamide Incorporating Pyrrolyl and Salicylyl Moieties and of Their Zinc(II) Complexes

Poly[(2-Hydroxy-4-Methoxy Benzophenone) Butylene] Resin and its Polychelates with Lanthanides(III): Synthesis and Characterization

Exploring the possibilities of double proton transfer in hydrazides: A theoretical approach

Contact Info

Product

Resources

About