Synthesis, characterization, and biological activity using computational study of synthesized monocyclic β-lactam ligands
Shweta Shweta,
Shabbir Muhammad,
Mahesh Kumar Mishra
et al.
Abstract:The synthesis of monocyclic β-lactam ligands, their spectral as well as the X-ray crystallographic analysis, computational study, and biological activity are all covered in this article. The characterization of all these ligands is completed through FT-IR, 1H NMR, 13C NMR and X-ray crystallography study. We applied computational study to analyze the biological activity of all the designed monocyclic β-lactam ligands (4a, 4b, 4c and 4d) against cancer. For this purpose, ligand-protein interactions are studied b… Show more
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