Abstract:This study is based on the synthesis and characterization of quinoline based peptides and heterocycles containing oxygen, nitrogen and sulfur atoms by using new catalysts. In addition, the biological activities of the novel small molecules is evaluated. A total of 71 small molecules were prepared by using multi-component reactions including Ugi and Kabachnik-Fields reaction. The Ugi four-component reaction was implemented for the synthesis of medicinally important 13 new quinolinyl-lipoyl peptides (QLPs) and o… Show more
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