Synthesis, Characterization and Biological Activities of 4-Thiazolidinone and 2-Azetidinone Derivatives

Swami, Mahesh B.; Kaminwar, Niteshkumar S.; More, Yogesh W.; Pathare, Pintu G.; Kótai, László; Kendrekar, Pravin K.; Pawar, Rajendra P.

doi:10.17628/ecb.2017.6.98-100

Cited by 4 publications

(1 citation statement)

References 5 publications

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“…Schiff bases discovered by Hugo Schiff in 1864 [1], have demonstrated that their structure contains the azomethine group -C=N-. Schiff bases, generally belongs to a very important class of organic compounds with wide range of a potential application, especially in hydrogenation and addition reactions as oxidation catalysts [2][3][4][5][6] and in anti-COVID-19 drug, anticancer drugs and electrochemistry as antibacterial and antiviral agents [7][8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Spectroscopic and Thermal Characterization and Antioxidant Activities of Three Schiff Bases Derived from Aminophenol

Yekhlef¹,

Benghanem²,

Foudia³

et al. 2023

IJHT

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The main objective of this work is synthesized three Schiff bases: (E)-2-(((2hydroxyphenyl)imino)methyl)-6-methoxyphenol (I), (E)-2-(((3-hydroxyphenyl) imino)-Methyl)-6-Methoxyphenol(II) and (e)-2-(((4-hydroxyphenyl)imino)methyl)-6amethoxyphenol(III) derivative of 2-hydroxy-3-methoxybenzaldehyde and ortho/meta / para-aminophenol, their structures were confirmed by spectroscopic methods: UV-Vis, FTIR, ( 1 H, 13 C NMR). Firstly, a thermogravimetric analysis (TGA/DTG) study of the composite Schiff bases proved them to be thermally stable. Secondly, the study of the biological properties of the synthesized compounds allowed the evaluation of the antioxidant activity by conventional methods (scavenging of the DPPH radical, and bleaching of ß-carotene). The results demonstrated a variable degree of inhibitory effects on the growth of synthesized Schiff bases.

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Section: Introductionmentioning

confidence: 99%

Synthesis, Spectroscopic and Thermal Characterization and Antioxidant Activities of Three Schiff Bases Derived from Aminophenol

Yekhlef¹,

Benghanem²,

Foudia³

et al. 2023

IJHT

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Azomethines based on ethyl 4-formyl-3,5-dimethyl-1H-pyrrole-2-carboxylate, its biological activity and reaction with thioglycolic acid

Mikhedkina,

Ananieva,

Sakhno

et al. 2023

Chem Heterocycl Comp

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Synthesis and characterization of some new thiazolidinone derivatives containing indole ring

Tomma

Ali

AL-Aliawi

2021

J. Phys.: Conf. Ser.

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Many new heterocyclic compounds including 4-thiazolidinones containing indole with triazole units were described. The new Schiff bases [VII]a, b and [VIII]a,b synthesized by condensation acid hydrazides [II],[VI] with different (aromatic) aldehydes in absolute ethanol. The refluxing equimolar amounts of the Schiff bases ([VII]a,b, [VIII]a,b) with thioglycolic acid in benzene led to get thiazolidin-4-ones derivatives ([IX]a,b and [X]a-d). Finally, the new derivatives [XI]a-c run out via the reacted compound [IX]a with different n-alkyl bromide (methyl bromide, ethyl bromide, and butyl bromide) in alkaline media.

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Synthesis, Characterization and Biological Activities of 4-Thiazolidinone and 2-Azetidinone Derivatives

Cited by 4 publications

References 5 publications

Synthesis, Spectroscopic and Thermal Characterization and Antioxidant Activities of Three Schiff Bases Derived from Aminophenol

Synthesis, Spectroscopic and Thermal Characterization and Antioxidant Activities of Three Schiff Bases Derived from Aminophenol

Azomethines based on ethyl 4-formyl-3,5-dimethyl-1H-pyrrole-2-carboxylate, its biological activity and reaction with thioglycolic acid

Synthesis and characterization of some new thiazolidinone derivatives containing indole ring

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