Synthesis, characterization and biocidal activity of some transition metal(II) complexes with isatin salicylaldehyde acyldihydrazones

Synthesis, Spectroscopic, Computational Structure Analysis, Molecular Docking, in vitro Antibacterial and in vivo Antipyretic Investigations of Transition Metal(II) Complexes

“…There are numerous metal complexes of hydrazone derivatives that exhibit antialgae, antifungal, antibacterial and antitumor activity, according to reports [9][10][11]. Although the polyfunctional ligand hydrazone can create more stable complexes with d-block elements, there are just a few articles that have been published that discuss unsymmetrical hydrazone ligands [12].…”

Synthesis and characterization of four N-acylhydrazones as potential O,N,O donors for Cu2+: An experimental and theoretical study

“…Hence, Cu 2+ complexes derived from NAHs of salicylaldehyde and related compounds have been widely investigated. The medicinal properties of these complexes include effective DNA binding [4] and cleavage [11]; a significant bacteriostatic effect [12]; anticancer [13], antifungal [14], antioxidant [15] activities; etc.…”

Synthesis, Spectroscopic Characterization And Antimicrobial Evaluation of Novel Nitrogen Containing Metal Complexes

“…Schiff bases are azomethine group (C=N) containing compounds which were first announced by Hugo Schiff in 1864 and synthesized by condensation of the primary amine with carbonyl compound [1]. Schiff bases remain the most extensively utilized organic compounds [2][3][4][5][6][7] and it has potential sites, such as nitrogen and other electron donors; it may be related to their stability, uses and applications in numerous scientific areas [1,2,4,5,[8][9][10]. For long periods of time, coordination chemistry of Schiff base ligands has been the topic of great interest.…”

“…Much interest has been focused on the hydrazone complexes to exhibit the coordinative behavior-microbial activity relationship and to their antiparasitic, fungicidal and bactericidal properties [8,20]. And this is because the strong ability of hydrazone part in chelating metal ions [7,8], whereas hydrazone contain two nitrogen atoms of different nature are associated and a C=N that is conjugated with alone pair of the terminal nitrogen atom [19]. The hydrazides and their derivatives are very important ligands and have attracted considerable attention recently, due to their several biological activities.…”