Synthesis, characterization, and antioxidant activity in vitro of selenium-Euryale ferox Salisb. polysaccharide

Dong, Fang; Zheng, Hu-Zhe; Jeong, Wooyoung; Chung, Sung Kwang; Qu, Zhongyuan; Zou, Xiang; Liu, Chen; Xiang, Qiong; Feng, Feng

doi:10.1186/s13765-021-00631-4

Cited by 8 publications

(8 citation statements)

References 47 publications

(41 reference statements)

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“…Furthermore, the protein contents of PPP and PPP-Cr(III) were 1.18% and 1.13%, indicating most of the proteins were removed completely by the Sevag reagent. Moreover, the surface and inner morphological structure were evidently different between PPP and PPP-Cr(III) by SEM and TEM results (Text S1 and Figure S1) [30,31].…”

Section: Physicochemical Propertiesmentioning

confidence: 98%

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Structural Characterization and Hypoglycemic Activity of a Novel Pumpkin Peel Polysaccharide-Chromium(III) Complex

Zhang

et al. 2022

Foods

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The aim of our study was to synthesize a pumpkin peel polysaccharide (PPP)-Cr(III) complex and investigate its hypoglycemic activity. Firstly, a novel PPP-Cr(III) complex with a Cr content of 23.77 mg/g was synthesized and characterized. Physicochemical characterization indicated that PPP-Cr(III) had some changes in chemical composition, monosaccharide composition, and morphological structure compared with PPP. The molecular weights of PPP-Cr(III) and PPP were 1.398 × 106 g/mol and 3.386 × 106 g/mol, respectively, showing a lower molecular weight after the introduction of Cr(III). Fourier transform infrared spectroscopy showed that a new characteristic absorption peak of Cr-O appeared at 534 cm−1 in PPP-Cr(III), indicating that Cr(III) was successfully complexed with PPP. Secondly, the hypoglycemic activity of PPP-Cr(III) based on α-glucosidase inhibitory and insulin resistance (IR)-HepG2 cells was evaluated. Compared with PPP, PPP-Cr(III) exhibited a more significantly α-glucosidase inhibitory activity. The IR-HepG2 cells confirmed an obvious increase in glucose consumption. Western blot analysis demonstrated that the treated IR-HepG2 cells were able to increase the protein levels of p-AMPK and p-GSK-3β, indicating that IR-HepG2 cells exerted hypoglycemic activity via the AMPK/GSK-3β signaling pathway. These results suggested that PPP-Cr(III) had good hypoglycemic activity, which could provide theoretical support for the development of novel hypoglycemic products.

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Section: Physicochemical Propertiesmentioning

confidence: 98%

“…The following supporting information can be downloaded at: https: //www.mdpi.com/article/10.3390/foods11131821/s1, Text S1 [30,31]: SEM and TEM analysis;…”

Section: Supplementary Materialsmentioning

confidence: 99%

Structural Characterization and Hypoglycemic Activity of a Novel Pumpkin Peel Polysaccharide-Chromium(III) Complex

Zhang

et al. 2022

Foods

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“…The in vitro antioxidant tests showed that Selenium-E. ferox may serve as an antioxidant by scavenging DPPH, ABTS, and OH and improving reduction capacity (Dong et al, 2021).…”

Section: Polysaccharidesmentioning

confidence: 99%

“…According to the ideal synthesis technique for Selenium‐ E. ferox (reaction time at 5 hr, reaction temperature at 81°C, and weight ratio of Na 2 SeO 3 to E. ferox polysaccharide at 0.9 g/g), the result showed that the Se content of Selenium‐ E. ferox was 2.915 mg/g. The in vitro antioxidant tests showed that Selenium‐ E. ferox may serve as an antioxidant by scavenging DPPH, ABTS, and OH and improving reduction capacity (Dong et al, 2021).…”

Section: Major Bioactive Compounds Of E Feroxmentioning

confidence: 99%

Euryale ferox , a prominent superfood: Nutritional, pharmaceutical, and its economical importance

Kapoor

Kaur

et al. 2022

Journal of Food Biochemistry

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Euryale ferox (also known as foxnut), belongs to the family Nymphaeaceae. It is mainly grown in India, China, Japan, and Korea. It is a highly nutritious food, abundant in nutritional and bioactive compounds such as carbohydrates, protein, fiber, vitamins, minerals, and polyphenols. It is considered a functional food owing to its various health benefits such as antidiabetic, antihyperlipidemic, antifatigue, hepatoprotective, cardioprotective, antimelanogenic, etc. E. ferox has immense potential in both food and non‐food industries. Regardless of being recognized as a superfood packed with nutritional as well as medicinal properties, it is still neglected, and there has not been much attention given to its cultivation. Therefore, in this review, the potential of E. ferox as a superfood has been explored to enhance its utilization in the development of different foods and make it available outside its growing area. Practical applications Euryale ferox is abundant in several macronutrients and micronutrients; and considered as a superfood in terms of various health benefits. E. ferox has the ability to be used in the development of different health, functional, and nutraceutical foods, which will open a new door for the food industry to combat with numerous diseases.

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“…The highlevel aspects of polysaccharide structure, such as chain flexibility and spatial conformation, are closely related to polysaccharide activity. To improve the biological activity of polysaccharides, we must investigate polysaccharide molecular modification and structural transformation [16].…”

Section: Introductionmentioning

confidence: 99%

Characteristics of selenium polysaccharide from sweet corncob and its effects on non-enzymatic glycosylation in vivo

Wang

Xiu

et al. 2022

Appl Biol Chem

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Selenium polysaccharide is an organic selenium compound, which has attracted much attention because of its unique biological properties. In the current study, a new selenium polysaccharide (Se-SCP) was synthesised, and its structure and effects on non-enzymatic glycosylation in vivo were studied. The molecular weight of Se-SCP was 9.02 g/mol, and its molecule was mainly composed of Man, Gal, GluA, Ara, Glu, Fuc, Rha, GalA, and Xyl. Selenium was present both as C–O–Se and Se=O. Compared with non-selenised sweet corncob polysaccharide (SCP) treatment, the blood glucose level in mice decreased considerably after Se-SCP treatment. Additionally, it improved oral glucose tolerance (OGTT) and significantly reduced the production of advanced glycation end-products (AGEs) (P < 0.05), compared with the model group. In addition, Se-SCP exhibited a positive effect on the morphology of the pancreas and liver. The current study elucidated the physiological and pharmacological effects of selenium polysaccharides and provided a basis for future studies on selenium polysaccharides.

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Synthesis, characterization, and antioxidant activity in vitro of selenium-Euryale ferox Salisb. polysaccharide

Cited by 8 publications

References 47 publications

Structural Characterization and Hypoglycemic Activity of a Novel Pumpkin Peel Polysaccharide-Chromium(III) Complex

Structural Characterization and Hypoglycemic Activity of a Novel Pumpkin Peel Polysaccharide-Chromium(III) Complex

Euryale ferox , a prominent superfood: Nutritional, pharmaceutical, and its economical importance

Characteristics of selenium polysaccharide from sweet corncob and its effects on non-enzymatic glycosylation in vivo

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