Synthesis, Characterization and Antimicrobial Screening of Benzene Sulfonamide, 4-Amino-N- (5-Methyl-3-Isoxazolyl) Monosilver Salt and Related Compounds

Herole, Ramesh; Velingkar, V. S.

doi:10.7439/ijpc.v1i2.135

Cited by 2 publications

(2 citation statements)

References 7 publications

(9 reference statements)

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“…Sulfonamide compounds identified as chemotherapeutic agents, possess a broad spectrum of biological properties 13 . Sulfanilamide is a potent antibiotic because this drug undergoes metabolic alterations in tissues 14 .…”

Section: Discussionmentioning

confidence: 99%

Untitled

2014

IJPSR

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Measurement of ultrasonic velocity in non-aqueous solution gives information about the behavior of solution such as molecular association and disassociation. The attraction and repulsion between the molecules of the components involved show considerable effect upon the physical and chemical properties of a solution such as density, viscosity, and ultrasonic velocity. The ultrasonic velocity data combined with density and viscosity provides the standard means for determining the acoustical parameters and internal pressure, free volume. The Specific acoustic impendence in solutions can be used as a tool to estimate the strength of intermolecular attraction. Internal pressure (πi) and free volume (Vf) are the transport properties, which are useful in understanding the intra and intermolecular interactions. Internal pressure gives an idea of the solubility characteristics. Sulphanilamide is a parent compound and also the potent antibiotic which is important in urinary tract infections and meningococcal meningitis profilaxes 1 . Another sample Sulphadiazine is the Sulphonamide potent antibiotic, and it is a competitive inhibitor of the bacterial enzyme dihydropteroate synthesis.

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Section: Discussionmentioning

confidence: 99%

Untitled

2014

IJPSR

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“…Herole et al, [7] reported Synthesis, characterization and antimicrobial screening of Benzene sulphonamide, 4-Amino-N-(5-Methyl-3-Isoxazolyl) Monosilver salt and related compounds. Mrinalini et.al [8] reported Mixed ligand cobalt (III) complexes with 1-Amidino-O-Methylurea and Amino Acids.Umesh et.al [9] Synthesis and Biological evaluation of some sulphonamide schiff's bases.…”

Section: Introductionmentioning

confidence: 99%

FT-IR, Acoustic, Thermodynamic and Docking Study of a Drug in a Peptide

Padmavathy¹

2018

IJCRR

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Peptides have a wide range of application in medicine and biotechnology. They regulate most physiological process, acting at some sites as endocrine or paracrine signals and at others as neurotransmitter or growth factors. Ultrasonic studies of solutions yield valuable information about the molecular interactions, the nature and strength of interactions since the ultrasonic velocity is highly sensitive to molecular structure. The ultrasonic velocity (U), density (ρ) and viscosity (h) measurements have been carried out for peptide with fixed concentration of the sulfa drug in non -aqueous solution of ternary mixture at different temperatures. Experimental data have been used to estimate the internal pressure (πi) and free volume (Vf). The results are discussed in terms of interionic/ intermolecular interaction.To study the biological activity of the investigation molecule, molecular docking was done to identify the hydrogen bond lengths and binding energy with different antimicrobial protein. In the present investigation, ternary system of peptide solutions are carried out and an attempt is made to corroborate the ultrasonic, antimicrobial and docking study.

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Synthesis, Characterization and Antimicrobial Screening of Benzene Sulfonamide, 4-Amino-N- (5-Methyl-3-Isoxazolyl) Monosilver Salt and Related Compounds

Cited by 2 publications

References 7 publications

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FT-IR, Acoustic, Thermodynamic and Docking Study of a Drug in a Peptide

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