Synthesis, Characterization and Antimicrobial Activity of Zinc Oxide Nanoparticles against Drug-Resistant Escherichia coli Isolated from Potable Water

Abstract

Nanoparticles have outstanding properties due to their small size. Their high surface-to-volume ratio facilitate them a better interaction with biomolecules. Metal oxide nanomaterials like CuO, Ag and ZnO have been in frequent use for several purposes. Their inherent ability and surface chemistry make them suitable for the antimicrobial agent against pathogens. In this regard, the present study focuses on the synthesis and antibacterial activity of ZnO-NPs against Enterotoxigenic Escherichia coli (ETEC). Synthesis of ZnO-NPs was achieved by chemical method followed by capping of citrate. This allowed the particles to be separate and monodispersed. After characterization, the synthesized ZnO-NPs were tested as antibacterial agent against ETEC. The time dependent growth inhibition was also performed. The synthesized ZnO-NPs were highly effective and showed bactericidal activity after 16 hours. The present study offers ZnO-NPs as a potential antimicrobial agent which can be used against ETEC.

Zn-containing Wollastonite with Well-defined Microstructural and Good Antifungal Activity

“…Specimens exposed to the stated microorganisms veri ed different antifungal properties as revealed in Table 3. It may be determined that the best antifungal activity was attributed to CZS5 (the higher concentrations of zinc oxide content) in agreement with early research of [29]. The clarifying antibacterial activity of the calcium silicate matrix doped with ZnO is an another promising reason for demonstrating their ability to transfer through the bacterial membrane along with destructing it [30].…”