Synthesis, characterization, and anticancer properties of rare earth complexes with Schiff base and o-phenanthroline

New Complexes of Lighter Trivalent Lanthanides With Indomethacin Anti-Inflammatory Drug: Synthesis, Thermal Properties and Spectroscopic Study in the Solid State.

“…According to different reports in the literature [12,28,29,32], these results suggest that indomethacin coordinates through the carboxylate group to the lighter lanthanides as a bidentate chelating ligand. The theoretical calculation of the infrared spectra for the lanthanum compound is in agreement with this interpretation.…”

Synthesis and Biological Studies of Some Lanthanide Complexes of Schiff Base

“…[4,[10][11][12] At the same time, studies show that some lanthanide complexes might have a potential role in the treatment of tumor cell lines, [13] so the design and synthesis of the lanthanide complexes as potential anticancer and antibacterial agents have received more attention. [14] In these complexes, tremendous interest has been attracted to the lanthanide complexes with organic ligands [15,16] because of the metal or ligands can be varied in an easily controlled way to facilitate the individual applications. [17] Schiff bases have been applied in many fields (e.g., anticancer, antibacterial, antiviral, antifungal, and other biological properties).…”

“…Because of the importance of lanthanide complexes and our interest in the synthesis of lanthanide complexes, [3,9,15,29,30] we report herein the synthesis, spectroscopic studies, thermal investigation, and biological activities of lanthanide complexes with isoniazid furalacylhydrazone and sodium salicylate, in continuation of our research to develop some new antitumor and antibacterial agents that may provide useful basis for the application in biological activities for lanthanide complexes and other related fields. [3] Experimental Materials Ln(NO 3 ) 3 ¢6H 2 O was purchased from Aladdin; RPMI 1640 and tetrazolium salt 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) were purchased from Sigma; fetal calf serum (FCS) was purchased from GiBCo, No.1165723; sodium dodecylsulfate (SDS)was purchased from Sino-American Biotechnology.…”

Investigation on coordination number and geometrical conformation of rare earth complexes with catenulate aminopolycarboxylic acid ligands

“…[1][2][3][4][5][6][7][8][9]. For instance, some Gd III complexes are used as contrast agents for magnetic resonance imaging (MRI) diagnoses since there are seven high-spin single D (1,4,3), which should be small for MCSAP.…”

“…For eightand ten-coordinate complexes, there is a close relationship between their geometrical conformation and MCSAP. When the second ligand above the square basal plane (5,6,9,8) in MCSAP is taken away, the nine-coordinate MCSAP will become an eightcoordinate square antiprism (SAP) conformation. Contrarily, when another coordinate atom as the tenth ligand is added above the square basal plane (1,4,3,7) in MCSAP, the nine-coordinate MCSAP will become a ten-coordinate bicapped square antiprism (BCSAP).…”