Synthesis, characterization and antibacterial activity of silver nanoparticles using Rhazya stricta

Abstract

BackgroundGreen synthesis of metallic nanoparticles has gained significant attention in the field of nanomedicine as an environment-friendly and cost-effective alternative in comparison with other physical and chemical methods. Several metals such as silver, gold, iron, titanium, zinc, magnesium and copper have been subjected to nanoformulation for a wide range of useful applications. Silver nanoparticles (AgNPs) are playing a major role in the field of nanomedicine and nanotechnology. They are widely used in diagnostics, therapeutic and pharmaceutical industries. Studies have shown potential inhibitory antimicrobial, anti-inflammatory and antiangiogenesis activities of AgNPs.MethodsAgNPs have been synthesized using silver nitrate and methanolic root extract of Rhazya stricta that belongs to the Apocynaceae family. Stability and dispersion of nanoparticles were improved by adding xylitol. Synthesized nanoparticles were characterized by UV–Vis spectroscopy, scanning electron microscopy, energy dispersive spectroscopy, X-ray diffractometer and Fourier transforms infrared spectroscopy. Furthermore, the antibacterial effect of the plant extract and the nanoparticles were evaluated against gram-positive (Bacillus subtilis) and gram-negative (Escherichia coli) bacteria.ResultsThe average size of AgNPs synthesized, was 20 nm with the spherical shape. Rhazya stricta based nanoparticles exhibited improved antibacterial activity against both gram-positive and negative strains.

Green Synthesis and Characterization of Silver Nanoparticles using Crude Extract of Crotalaria burhia

“…Abdel-Aziz and his collegues also confirmed the antioxidant and antibacterial activity of silver nano particles of Chenopodium morale leaf [18]. Antibcterial activity of silver Nano particles of many plants have been confirmed like Cestrum nocturnum [19], Rhazya stricta [20], Ferula gumosa, Ferula latisecta, Teucrium polium and Trachomitum venetum leaves and stems extract [21], Zea mays [22] and Malus domestica [23] etc.…”

Nanoparticles: Synthesis, Morphophysiological Effects, and Proteomic Responses of Crop Plants

“…The crystal lattice structure of synthesized copper NPs was achieved through Morganella [49]. Silver NPs with spherical and cubic shaped having crystalline nature were synthesized using extracts of Litchi chinensis [50], Eucalyptus macrocarpa [51], and Rhazya stricta [52]. Iron NPs were synthesized using leaf extract of barberry, Elaeagnus angustifolia, saffron, Ziziphus jujube [53], grape tree [54], and green tea [55].…”

Biosynthesis and Antimicrobial activities of Silver Nanoparticles (AgNPs) by using Leaf Extracts of Tagetes erecta (Marigold) and Tridax procumbens (Tridax)

“…A comparative investigation was performed by taking consideration into the antimicrobial and antifungal activities of the raw leaf extracts and the synthesized AgNPs from the respective extracts against five bacteria such as; Bacillus subtilis (Gram +ve), Escherichia coli (Gram -ve) (Shehzad A et al, 2018), Klebsiella pneumonia (Gm -ve), Salmonella typhimurium (Gm -ve), Staphylococcus aureus (Gm +ve) and one fungus named Asperigillus niger procured from American type culture collection (ATCC). Agar Well-diffusion method was applied for testing each type of plant leaf extract and their respective AgNPs containing solution (Premasudha P. et al, 2015).…”