Synthesis, Characterization, and Antibacterial Activity of Schiff Bases Derived From Thiosemicarbazide, 2-Acetyl Thiophene and Thiophene-2 Aldehyde

Mohan, Chandra; Kumar, Vinod; Kumari, Sarla

doi:10.7897/2230-8407.097141

Cited by 13 publications

(12 citation statements)

References 8 publications

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“…Copper(II) heterocyclic thiosemicarbazone complexes have been extensively studied for their antimicrobial, anticancer, and antiviral properties [30][31][32][33][34][35]. However, little attention has been paid to their use as a single source precursor for the preparation of Cu x S y nanoparticles.…”

Section: Introductionmentioning

confidence: 99%

Copper (II) Heterocyclic Thiosemicarbazone Complexes as Single-Source Precursors for the Preparation of Cu9S5 Nanoparticles: Application in Photocatalytic Degradation of Methylene Blue

et al. 2022

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In this study, two copper(II) complexes, [Cu(C6H8N3S2)2]Cl2 (1) and [Cu(C7H10N3S2)2]Cl2·H2O (2), were synthesized from 2-(thiophen-2-ylmethylene)hydrazine-1-carbothioamide (L1H) and 2-(1-(thiophen-2-yl)ethylidene)hydrazine-1-carbothioamide (L2H) respectively and characterized using various spectroscopic techniques and elemental analyses. The as-prepared complexes were used as single-source precursors for the synthesis of oleylamine-capped (OLA@CuxSy), hexadecylamine-capped (HDA@CuxSy), and dodecylamine-capped (DDA@CuxSy) copper sulphide nanoparticles (NPs) via the thermolysis method at 190 °C and 230 °C and then characterized using powder X-ray diffraction (p-XRD), UV-visible spectroscopy, transmission electron microscopy (TEM), and scanning electron microscopy (SEM). The p-XRD diffraction patterns confirmed the formation of crystalline rhombohedral digenite Cu9S5 with the space group R-3m. The TEM images showed the formation of nanoparticles of various shapes including hexagonal, rectangular, cubic, truncated-triangular, and irregularly shaped Cu9S5 nanomaterials. The SEM results showed aggregates and clusters as well as the presence of pores on the surfaces of nanoparticles synthesized at 190 °C. The UV-visible spectroscopy revealed a general blue shift observed in the absorption band edge of the copper sulphide NPs, as compared to bulk CuxSy, with energy band gaps ranging from 2.52 to 3.00 eV. Energy-dispersive X-ray spectroscopy (EDX) confirmed the elemental composition of the Cu9S5 nanoparticles. The nanoparticles obtained at 190 °C and 230 °C were used as catalysts for the photocatalytic degradation of methylene blue (MB) under UV irradiation. Degradation rates varying from 47.1% to 80.0% were obtained after 90 min of exposure time using only 10 mg of the catalyst, indicating that Cu9S5 nanoparticles have potential in the degradation of organic pollutants (dyes).

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Section: Introductionmentioning

confidence: 99%

Copper (II) Heterocyclic Thiosemicarbazone Complexes as Single-Source Precursors for the Preparation of Cu9S5 Nanoparticles: Application in Photocatalytic Degradation of Methylene Blue

et al. 2022

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“…Therefore, these results confirmed the formation of Schiff base ligand. [28][29][30][31][32][33] Table-3: Electronic Spectral Data of Schiff Base Ligand and its Metal Complexes…”

Section: Electronic Spectra and Magnetic Susceptibilitymentioning

confidence: 99%

Synthesis, Characterization, Antimicrobial and Anti-Inflammatory Studies of Some Novel Schiff Base Metal Complexes Derived From the Drug, Diclofenac

Shilpa¹,

Shivaprasad²,

Archana³

2021

RJC

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The synthesis of Schiff base transition metal complexes always appears to be fascinating because of the possibility of obtaining coordination compounds of unusual structure and stability. These compounds possess special attention in the field of pharmaceuticals because of their wide spectrum of biological applications. Schiff base complexes form versatile compounds which actively take part in metalloenzymes and also can act as biomimetic models because of their closeness to natural proteins and enzymes. Hence, the present paper mainly aims in the synthesis of Schiff base ligand by modifying the functional group of the drug, diclofenac and using that Schiff base ligand four novel metal complexes of Cu(II), Co(II), Ni(II), and Zn(II) were prepared. The nature of bonding and the stereochemistry of the metal complexes can be deduced from elemental analyses, molar conductance, magnetic susceptibility, IR, electronic, 1 H NMR and Mass. The analytical data reveals that the metal to ligand ratio is 1:2. Due to lower molar conductivity values, the metal complexes are considered nonelectrolytes. The spectral analysis data describes that all the metal complexes possess octahedral geometry. The drug diclofenac synthesized Schiff base ligand and novel metal complexes were subjected to antimicrobial as well as anti-inflammatory activities. The Schiff base ligand and metal complexes show promising biological activities.

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“…Schiff bases derived from thiosemicarbazide may be very useful as ionophores because of their significant electrochemical and biochemical activity in liquid membrane. Schiff bases are the products of condensation of arylamines and carbonyl compounds [9]. They are quite stable and versatile intermediates for preparation of a number of important medicinal compounds.…”

Section: Introductionmentioning

confidence: 99%

Untitled

2024

MACIJ

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The main objective of this work is to provide information on the development of ion selective electrodes (ISEs) based on PVC membrane by incorporating Schiff base ligands and their complexes as ionophores for sensing different metals ion. Ion selective electrodes can be prepared and the electrodes performance may optimized by varying the amounts of PVC, plasticizers and cation/anion excluders. Various characteristic features of chemical sensors with different parameters such as response time, selectivity, lifetime and pH effect on sensor response have been reported. The proposed ISEs have been successfully applied to determine cations and anions and as electrode in potentiometric titrations.

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Synthesis, Characterization, and Antibacterial Activity of Schiff Bases Derived From Thiosemicarbazide, 2-Acetyl Thiophene and Thiophene-2 Aldehyde

Cited by 13 publications

References 8 publications

Copper (II) Heterocyclic Thiosemicarbazone Complexes as Single-Source Precursors for the Preparation of Cu9S5 Nanoparticles: Application in Photocatalytic Degradation of Methylene Blue

Copper (II) Heterocyclic Thiosemicarbazone Complexes as Single-Source Precursors for the Preparation of Cu9S5 Nanoparticles: Application in Photocatalytic Degradation of Methylene Blue

Synthesis, Characterization, Antimicrobial and Anti-Inflammatory Studies of Some Novel Schiff Base Metal Complexes Derived From the Drug, Diclofenac

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