Synthesis, characterisation and biological investigation of some third-row elements with halo- substituted coumarin schiff base with N and O as donors

Abstract

The present work involves in the synthesis, spectral characterisation and the biological analysis of the metal complexes which were derived from 3-Chloro-8-formyl-7-hydroxy-4-methylcoumarin and benzylamine. The molar conductivity values indicated that the complexes are non-electrolytes. Elemental analysis was carried out to assign the [ML2(H2O)2] stoichiometry to the metal complexes, where M=Co (II), Ni (II) and Cu(II) and L=deprotonated ligand. The IR data confirmed coordination of metal ions to the ligand. The presence of a coordinated water molecule was investigated by thermal studies and the electronic spectral results were helpful in assigning the geometry to synthesised complexes. The both Schiff base and the derived metal complexes were subjected various biological activities to check their potency.