Synthesis, biological and catalytic activity of silver nanoparticles generated and covered by oxidized pullulan

Constantin, Marieta; Spiridon, Maria; Ichim, Daniela Luminița; Darabă, Oana Maria; Suflet, Dana Mihaela; Ignat, Maria; Fundueanu, Gheorghe

doi:10.1016/j.matchemphys.2022.127141

Cited by 14 publications

(7 citation statements)

References 81 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The FT-IR spectrum of OP confirmed the successful oxidation of pullulan by the presence of the peak at 1733 cm −1 , characteristic of the aldehyde group in the dialdehyde pullulan [29,32,33]. Also, the band at 872 cm −1 was attributed to the -C-H out-of-plane bending from resultant hemiacetal bonds between aldehyde groups and neighbor hydroxyl groups [62]; the sharper peak at 1035 cm −1 owing to C-O-C stretching is a result of the hydration of aldehydes [63]. The FT-IR spectrum of the CS 1 /PVA 1 /OP 1 hydrogel (Figure 2a) shows all the abovementioned characteristic peaks for pure components.…”

Section: Preparation and Preliminary Characterization Of The Hydrogelsmentioning

confidence: 98%

Tri-Component Hydrogel as Template for Nanocrystalline Hydroxyapatite Deposition Using Alternate Soaking Method for Bone Tissue Engineering Applications

Pelin,

Popescu,

Calin

et al. 2023

Gels

Self Cite

View full text Add to dashboard Cite

Composite hydrogels containing apatite-like particles can act as scaffolds for osteoblast proliferation, with applications in bone tissue engineering. In this respect, porous biocompatible hydrogels were obtained from chitosan, oxidized pullulan, and PVA in different ratios. The stability of the hydrogels was ensured both by covalent bonds between aldehyde groups of oxidized pullulan and free amino groups of chitosan, and by physical bonds formed during freeze–thaw cycles and lyophilization. The deposition of calcium phosphates was performed by alternate soaking of the porous hydrogels into solutions with calcium and phosphate ions, assuring a basic pH required for hydroxyapatite formation. The mineralized hydrogels were characterized using FTIR spectroscopy, scanning electron microscopy, X-ray diffraction, and thermogravimetric analysis, showing that inorganic particles containing between 80 and 92% hydroxyapatite were deposited in a high amount on the pore walls of the polymeric matrix. The composition of the organic matrix influenced the crystallization of calcium phosphates and the mechanical properties of the composite hydrogels. In vitro biological tests showed that mineralized hydrogels support the proliferation of MG-63 osteoblast-like cells to a greater extent compared to pristine hydrogels.

show abstract

Section: Preparation and Preliminary Characterization Of The Hydrogelsmentioning

confidence: 98%

Tri-Component Hydrogel as Template for Nanocrystalline Hydroxyapatite Deposition Using Alternate Soaking Method for Bone Tissue Engineering Applications

Pelin,

Popescu,

Calin

et al. 2023

Gels

Self Cite

View full text Add to dashboard Cite

show abstract

“…Thus, in the CS/OP 1 spectrum (Figure 2a), the large band at 3352 cm −1 was assigned to O-H and N-H stretching, as well as the intra-and inter-molecular hydrogen bonds; the bands at 2963-2854 cm −1 to C-H asymmetric and symmetric stretching from CH 2 and the CH groups; and the peaks from 1643 cm −1 , 1591 cm −1 , 1543 cm −1 , and 1313 cm −1 were attributed to the C=O stretching of amide I, amines, and secondary amides, and C-N stretching (amide III), respectively [61]. The peaks at 1728 cm −1 and 1234 cm −1 are related either with the lactic acid present in the hydrogel network [62] or with residual -CH=O groups of the OP [40]. At 1456, 1414, and 1375 cm −1 the asymmetric and symmetric vibrations of -COO − groups along with O-H bending in the COO − anion are present.…”

Section: Morphology and Porositymentioning

confidence: 98%

“…The degree of oxidation of the OP was determined according to Constantin et al [40] by the hydroxylamine hydrochloride method [90]. In practical terms, the hydrochloride released after the reaction of 0.1 g of OP with NH 4 OH•HCl (25 mL, 0.25 M) at pH 4 was determined by potentiometric titration with a standard NaOH solution (0.1 N).…”

Section: Determination Of the Degree Of Oxidationmentioning

confidence: 99%

“…properties [37]. The oxidation of P has been reported by using TEMPO [38] or periodate [39,40], when carboxyl or aldehyde groups are introduced to the main chain. Reactive aldehyde groups could form stable hydrogels by (hemi)acetal bonds [41] or by Schiff base bonds [42,43] when they react with the amino groups in a similar way to glutaraldehyde.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Chitosan–Oxidized Pullulan Hydrogels Loaded with Essential Clove Oil: Synthesis, Characterization, Antioxidant and Antimicrobial Properties

Suflet,

Constantin,

Pelin

et al. 2024

Gels

Self Cite

View full text Add to dashboard Cite

Emulsion hydrogels are promising materials for encapsulating and stabilizing high amounts of hydrophobic essential oils in hydrophilic matrices. In this work, clove oil-loaded hydrogels (CS/OP-C) are synthesized by combining covalent and physical cross-linking approaches. First, clove oil (CO) was emulsified and stabilized in a chitosan (CS) solution, which was further hardened by Schiff base covalent cross-linking with oxidized pullulan (OP). Second, the hydrogels were subjected to freeze–thaw cycles and, as a result, the clove oil was stabilized in physically cross-linked polymeric walls. Moreover, due to cryogelation, the obtained hydrogels exhibited sponge-like porous interconnected morphology (160–250 µm). By varying the clove oil content in the starting emulsion and the degree of cross-linking, the hydrogels displayed a high water retention capacity (swelling ratios between 1300 and 2000%), excellent elastic properties with fast shape recovery (20 s) after 70% compression, and controlled in vitro clove oil release in simulated skin conditions for 360 h. Furthermore, the prepared clove oil-loaded hydrogels had a strong scavenging activity of 83% and antibacterial and antifungal properties, showing a bacteriostatic effect after 48 and 72 h against S. aureus and E. coli. Our results recommend the new clove oil-embedded emulsion hydrogels as promising future materials for application as wound dressings.

show abstract

“…Covalent attachment, surface adsorption ➢Improve stability and oxidation resistance of nanoparticles. 86 ➢Improve nanoparticle dispersion stability, bioavailability and cytotoxicity.…”

Section: Capping Agent Morphology and Crystallite Sizementioning

confidence: 99%

Functionalized nanoparticles: Tailoring properties through surface energetics and coordination chemistry for advanced biomedical applications

et al. 2023

View full text Add to dashboard Cite

show abstract

Synthesis, biological and catalytic activity of silver nanoparticles generated and covered by oxidized pullulan

Cited by 14 publications

References 81 publications

Tri-Component Hydrogel as Template for Nanocrystalline Hydroxyapatite Deposition Using Alternate Soaking Method for Bone Tissue Engineering Applications

Tri-Component Hydrogel as Template for Nanocrystalline Hydroxyapatite Deposition Using Alternate Soaking Method for Bone Tissue Engineering Applications

Chitosan–Oxidized Pullulan Hydrogels Loaded with Essential Clove Oil: Synthesis, Characterization, Antioxidant and Antimicrobial Properties

Functionalized nanoparticles: Tailoring properties through surface energetics and coordination chemistry for advanced biomedical applications

Contact Info

Product

Resources

About