“…The incorporation of dihydroxyphenyl moiety in organic compounds, not limited to 1,3,4-thiadiazole has attracted considerable attention due to its naturally derived characterization and wide prevalence in pesticides and medicinal compounds. In our previous work, many heterocyclic compounds containing 2,4-dihydroxyphenyl moiety were reported with good fungicidal, antibacterial, and antitumor activities [22][23][24]. This substituent seems to be crucial in the biological effects.…”