Synthesis, anti-bacterial, anti-asthmatic and anti-diabetic activities of novel N-substituted-2-(4-phenylethynyl-phenyl)-1H-benzimidazoles and N-substituted 2[4-(4,4-dimethyl-thiochroman-6-yl-ethynyl)-phenyl)-1H-benzimidazoles

Antibacterial Screening of New Synthesis Schiff Base having Benzimidazole Moiety

“…Some benzimidazole derivatives have been noted as thyroid receptor stimulants. Also widely used as drugs such as proton pump inhibitor omeprazole [25]. Schiff bases considered as important class of organic compounds, especially in the medicinal and pharmaceutical field.…”

“…Benzimidazole is a versatile pharmacophore producing a different range of biological activities [2], including analgesic [3] and antiinflammatory [4][5][6]. Benzimidazole derivatives have found the application in different therapeutic areas including, antihypertensive [7], antiviral [8,9], antifungal [10][11][12], anticancer [13][14][15], antitubercular [16,17], antioxidant [18,19], antimicrobial [20][21][22][23], antibacterial [24][25][26]. Benzimidazole derivatives are highly active against several viruses such as HIV, herpes (HSV-1), RNA, influenza and human cytomegalovirus (HCMV) [27].…”

Facile and convenient new synthesis of imidazobenzimidazol-2-one and pyrimidobenzimidazol-2,3-dione derivatives

“…Several benzimidazoles have been reported as antiviral 5 , anticoagulant 6 , antiinflammatory 7 , antibacterial 8 , anticancer 9 and antiproliferatif agents 10 . Moreover heterocycles derivatives of benzimidazoles systems have been tested as a potential antimicrobial 11 , antibacterial 12 , antimalarial 13 , antineoplastic 14 , antioxidant 15 , antidiabetic 16 , anticonvulsant 16 and anti-hepatitis C virus agents 17 .…”

Synthesis of Some Novel N-Substituted 2-(4-Bromo-Phenoxymethyl)-1h-Benzimidazole Derivatives and Their Antimicrobial Evaluation

“…Some of the benzimidazole derivatives are marketed as anti-fungal 4 , anti-helmintic 5 and anti-psychotic 6 drugs and other derivatives have been found to possess some interesting bioactivities such as antitubercular 7 , anti-cancer 8 , HIV-Inhibitors 9 , Anti-Hypertensive Agent 10 , Anti-Inflammatory activity 11 , Anti-allergic activity 12 , Anti-diabetic Activity 13 , Anticonvulsant activity 14 and DNA Inhibitory Activity 15 etc. Considering the immense biological importance of benzimidazole derivatives, we now synthesized some novel class of benzimidazole derivatives and their biological activity screening studies.…”