Synthesis and Surface and Antimicrobial Properties of Novel Cationic Surfactants

Abstract

A series of surfactants with tuned polarity were prepared, including a new class of compounds: gluco-pyridinium surfactants. Pure anomers were obtained by chromatographic separation. The conductivity and surface tension of surfactant solutions in water were measured, and provided interesting information regarding their aggregation behavior. Peculiarities were observed in the premicellar range. Tensidic parameters correlated with antimicrobial activity. A few parameters, mainly the hydrophobicity of the headgroup, may play a role in finding more efficient antimicrobial structures.

Synthesis, Physicochemical Characterization, and Interaction with DNA of Long‐Alkyl‐Chain Gemini Pyridinium Surfactants

“…[10,60] The addition of concentrated surfactant solutions by aC RISON automatic burette to pure water and the collection of the conductivity data were performed by using ac omputer-controlled automated system, working with ah omemade program written in Quick Basic (available from the author).…”

Synthesis and Antimicrobial Activity of Quaternary Ammonium Silane Coupling Agents

“…Table 1 shows the stoichiometry of the reactants, reaction times, yields, and properties of n-X. The spectra data are given in 2.5.2 18,22 . Table 2 lists the results of the MIC tests against 12 kinds of fungi and bacteria.…”

Structure-antimicrobial activity relationship and action mechanism of dimeric quaternary ammonium amphiphiles

“…Among numerous antimicrobial agents, small-molecular-weight quaternary ammonium compounds (QACs) are extensively used as antimicrobial agents because of wide spectrum of antimicrobial activity against bacteria (both gram positive and gram negative), fungi, and certain viruses [3][4][5] . Dimeric amphiphiles, which are composed of two hydrophobic quaternary ammonium head groups and two hydrophilic chains, appear to be much better antibacterial activity than the corresponding conventional mono-QACs [6][7] .…”