Synthesis and study of the antianemic activity of p-ferrocenylphenol

Askarov, Ibragim; Kirgizov, Sh. M.; Nurimdinova, G. T.

doi:10.1007/bf00769649

Cited by 7 publications

(3 citation statements)

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“…The development of highly effective medicinal preparations for the treatment of anemia [Askarov I. R. 1989] and diseases of central neurosystem remains one of the important problems of modern medicine. The role of magnesium, iron, manganese, thiamine, riboflavin, niacin, and pantothenic acid, which play an important role in the functioning of the central nervous system, in glucose metabolism, as well as the importance of glucose metabolism.…”

Section: Discussionmentioning

confidence: 99%

Ethnobotanical Study of Acclimatized Lavender in Uzbekistan

Ibrokhim Rahmonovich Askarov,

Nabijon Alijonovich Razzakov,

Jasur Jamoldinovich Xomidov

et al. 2023

J. Adv. Zool.

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Rare plants are being introduced in the temperate climate of Uzbekistan for the purpose of increasing the stock of medicinal plants, wide use of natural means in maintaining the health of the population, development of the porphyry industry, and elimination of environmental problems. Including medicinal lavender (Lavandula officinalis L) seeds were planted in open field plantations and greenhouses in Pakhtaabad, Andijan and Yozhiovan districts of Fergana Valley, and morphobiological changes were studied. The generative and vegetative stages of the introduction process were analyzed. The plant introduction was successful. In order to scientifically justify the use of localized Lavandula officinalis in folk medicine, the composition of the macroelements of the above-ground part of the plant was determined using modern physico-chemical research. Based on the results of the conducted research, it is aimed to scientifically substantiate that it is possible to get good results by using the medicinal lavender plant in the treatment of diseases such as frequent nervousness, nervous system fatigue, which is increasing among the population.

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Section: Discussionmentioning

confidence: 99%

Ethnobotanical Study of Acclimatized Lavender in Uzbekistan

Ibrokhim Rahmonovich Askarov,

Nabijon Alijonovich Razzakov,

Jasur Jamoldinovich Xomidov

et al. 2023

J. Adv. Zool.

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“…It is an integral part of red blood cells, enabling their proper function. Iron actively participates in cellular gas exchange and facilitates the oxidation process of substances through its ability to bind with oxygen (Anvar 2004; Askarov et al 1988;Ganieva et al 1994;Mamarakhmonov et al 2017).…”

Section: Analysis Of Biogenic Elementsmentioning

confidence: 99%

Ethnobotany, medicinal utilization and analysis of biogenic elements and flavonoids of Apium graveolens and Tussilago farfara from Uzbekistan

Islomova,

Asqarov,

Bussmann

et al. 2023

Ethnobot. Res. App.

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Background: Plants are a rich source of both organic and inorganic substances that play a crucial role in determining their therapeutic effects. Within each medicinal plant, a diverse array of chemical compounds and trace elements can be found, contributing to its wide spectrum of healing properties. It is important to highlight that certain chemical element found in medicinal plants are essential for sustaining life processes. Elements such as calcium (Ca), potassium (K), sodium (Na), sulfur (S), iron (Fe), silicon (Si), manganese (Mn), magnesium (Mg), and zinc (Zn) are involved in nearly all biochemical processes within the body. They play crucial roles in regulating energy metabolism, primary and secondary metabolism, as well as hormonal regulation occurring within cells. This article examines the ethnobotany, medicinal utilization and analysis of biogenic elements and flavonoids of Apium graveolens and Tussilago farfara from Uzbekistan. Methods:The determination of biogenic elements in food products has been carried out using the plasma inductively coupled mass spectrometry method (ICP-MS). The reagents employed in the process included Standard No. 3, which contains multiple elements (29 elements for mass spectrometry). Additionally, the standards encompassed mercury, nitric acid, hydrogen peroxide, bi-distilled water, and argon gas (with a purity of 99.995%). The samples were subjected to analysis using the Agilent-1200 HPLC method with a diode detector, operating in the isocratic elution mode. The mobile phase consisted of a mixture of acetonitrile and buffer solution in a ratio of 70:30. The eluent flowed at a volumetric flow rate of -1.0 ml/min, and 10 µl of the sample was injected. Detection was performed at a wavelength of 254 nm. The chromatographic column used was the Eclipse XDB-C18, with dimensions of 5.0 microns and 4.6×250 mm. The thermostat temperature was maintained at 300°C.Results: Analyzing the study results we observed that all samples contained more than 18 elements: Highest concentration of Sodium, Magnesium, Potassium, Calcium, Iron, Copper, Zinc in the seeds of Apium graveolens, followed by Tussilago farfara and A. graveolens leaves. As a result of the analysis conducted on extracts of Tussilago farfara and Apium graveolens, six phenolic flavonoid compounds were successfully isolated. One particular flavonoid, apigenin, exhibits a retention time shift during analysis, indicating its presence. The relatively high concentrations of flavonoids such as rutin, quercetin, and dihydroquercetin further contribute to the significance of studying these plants. Conclusion:The conducted studies focused on the analysis of nutrients and flavonoids present in plants such as Tussilago farfara and Apium graveolens. Additionally, these medicinal plants were found to be rich in essential elements such as calcium, magnesium, potassium, and iron. Building upon these findings, the proposal was made to develop novel dietary supplements aimed at providing relief in the treatment of bone-related disorders, cardi...

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“…After electrochemical oxidation of the Fe(II) ion to Fe(III) a one-electron transfer from the phenol moiety takes place, in which a proton is transferred simultaneously [20]. Furthermore, 4-ferrocenylphenol shows an antianemic activity in mongrel rabbits [21]. …”

Section: Introductionmentioning

confidence: 99%

New enzymatically polymerized copolymers from 4-tert-butylphenol and 4-ferrocenylphenol and their modification and inclusion complexes with β-cyclodextrin

Mondrzyk¹,

Mondrzik²,

Gingter³

et al. 2012

Beilstein J. Org. Chem.

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SummaryThe enzymatically catalyzed synthesis of a copolymer of 4-tert-butylphenol and 4-ferrocenylphenol by horse radish peroxidase (HRP) in the presence of H2O2 in a 1,4-dioxane/water system is described. Furthermore, polymer-analogous alkylation of the free hydroxy groups and subsequent click reaction with mono-6-azido-6-desoxy-β-cyclodextrin (N3-β-CD) was carried out. The formation of inter- and intramolecular inclusion complexes was investigated by DLS measurement.

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Synthesis and study of the antianemic activity of p-ferrocenylphenol

Cited by 7 publications

References 0 publications

Ethnobotanical Study of Acclimatized Lavender in Uzbekistan

Ethnobotanical Study of Acclimatized Lavender in Uzbekistan

Ethnobotany, medicinal utilization and analysis of biogenic elements and flavonoids of Apium graveolens and Tussilago farfara from Uzbekistan

New enzymatically polymerized copolymers from 4-tert-butylphenol and 4-ferrocenylphenol and their modification and inclusion complexes with β-cyclodextrin

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