Synthesis and structure of pyridine-containing hexahydrobenzofuranone oximes

Abstract

Previously unknown pyridine-containing hexahydrobenzofuranone oximes were synthesized by reactions of 1-nitro-2-(3-pyridyl)ethene with dimedone and dihydroresorcinol, and their structure was studied by physicochemical methods. According to X-ray diffraction data, 2-hydroximino-6,6-dimethyl-3-(3-pyridyl)-2,3,4,5,6,7-hexahydrobenzofuran-4-one has an almost planar five-membered heteroring and the pyridine ring almost perpendicular to it; the six-membered ring has a sofa conformation.