Synthesis and Structure—Activity Relationships of 3H‐Quinazolin‐4‐ones and 3H‐Pyrido[2,3‐d]pyrimidin‐4‐ones as CXCR3 Receptor Antagonists.

Abstract

Fused pyrimidine derivatives R 0515 Synthesis and Structure-Activity Relationships of 3H-Quinazolin-4-ones and 3H-Pyrido[2,3-d]pyrimidin-4-ones as CXCR3 ReceptorAntagonists. -(STORELLI, S.; VERZIJL, D.; AL-BADIE, J.; ELDERS, N.; BOSCH, L.; TIMMERMAN, H.; SMIT, M. J.; DE ESCH, I. J. P.; LEURS*, R.; Arch. Pharm. (Weinheim, Ger.) 340 (2007) 6, 281-291; Leiden/Amsterdam Cent. Drug Res., Div. Med. Chem., Vrije Univ., NL-1081 HV Amsterdam, Neth.; Eng.) -A. Forchert 41-136