Synthesis and stereochemistry of some novel dihydropyrrolo[3,4-c]pyrazoles

Novel sydnone derivatives carrying azidomethyl-1,2, 4-oxadiazole unit and their 1,3-dipolar cycloadditions

“…[7][8][9][10][11][12] On the other hand, triazole rings have also attracted remarkable attention due to their biological activities such as antifungal, anti-convulsant agents and especially popular in designing anticancer agents. [13][14][15][16][17] 1,3-Dipolar cycloaddition route is a valuable process to assemble molecules having fragments in biologically active agents of five-membered nitrogen heterocycles. From a synthetic standpoint, it may be considered worthy and in principle, available by a sequence involving sydnone functionalization with azido group followed by cycloaddition.…”