Synthesis and spectroscopy of the Tröger’s base derived from 2-aminoacridine

Abstract

The analogs of the Tröger's base,7,7,16,3',4'-f]-[1,5]-diazocine was prepared starting from 2-aminoacridine instead of 3-aminoacridine. The new compound, 7,17-methano-6,7,16,17-tetrahydro-diacridino-[2,1-b:2',1'-f]-[1,5]-diazocine, has been fully characterized by 1 H-and 13 C-NMR spectroscopies using mono-and bi-dimensional techniques. Other aminoacridine derivatives failed to afford Tröger's bases.