Synthesis and spectroscopic characterization of new tetradentate Schiff base and its coordination compounds of NOON donor atoms and their antibacterial and antifungal activity

Abdallah, Sayed M.; Zayed, M.A.; Mohamed, Gehad G.

doi:10.1016/j.arabjc.2010.02.006

Cited by 93 publications

(44 citation statements)

References 28 publications

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“…[20] A notable development in biological fields have been achieved by zinc Schiff base complexes such as Zn(II) complexes of 3-(4-5-(4-chlorophenyl)diazenyl)-2-hydroxybenzylideneamino (phenylimino)methyl)-4H-chromen-4-one as antibacterial agent, [21] zinc complexes of Schiff base ligand entitled as (S)-2-((1-phenylethylimino)methyl)phenol and (R)-2-(1-phenylethylimino)methyl)phenol as antioxidant, [22] and complexes of tetradentate Schiff bases ligand (H 2 L) with NOON donor atoms as antifungal agent. [23] For as much as in many metalloproteins, metals exist in asymmetrical environments [24][25][26] and zinc ions have suitable compatibility with most of biological organs. In continuation of our previous reports, [27][28][29] in this research, synthesis and spectroscopic characterization of a new series of zinc complexes containing an asymmetric Schiff base ligand will be interpreted and ultimately their antibacterial activities of them against two Gram-negative bacteria, Escherichia coli (ATCC 25922) and Pseudomonas aeroginosa (ATCC 9027), and two Grampositive bacteria, Staphylococcus aureus (ATCC 6538) and Bacillus subtilis, were evaluated.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization, and Antibacterial Activities of Some New Zinc Coordination Compounds of an Asymmetric Bidentate Schiff Base

Montazerozohori

Hoseinpour

Naghiha

et al. 2015

Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-

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An asymmetrical Schiff base ligand with two position for coordination to metal was obtained by condensation reaction between propane-1,2-diamine and (E)-3-(4-(dimethylamino)phenyl)acrylaldehyde. Characterization of the ligand and its Zn(II) complexes were performed suitably by means of the elemental analysis, FTIR, 1 H, 13 C NMR, UV-visible, melting points, and molar conductance. Lowering of the iminic bond energy, red shifts of electronic transition bands, and down fielded azomethine proton signals well confirm coordination of ligand to zinc center. All compounds were stable at room temperature for the many long times. All complexes were suggested to be nonelectrolytes due to low molar conductivities. After characterization, antibacterial properties of all compounds have been studied against two Gram-negative bacteria, Escherichia coli (ATCC 25922) and Pseudomonas aeroginosa (ATCC 9027), and two Gram-positive bacteria, Staphylococcus aureus (ATCC 6538) and Bacillus subtilis. The ligand and Zn(II) coordination compounds demonstrated acceptable antibacterial activities. Zinc complexes showed higher activity than the parental ligand. The compounds inhibited the growth of Gram-negative more efficiently than Gram-positive bacterial strains. MIC and MBC of all compounds as alternative data for antibacterial activity were reported in mg/mL.

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Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization, and Antibacterial Activities of Some New Zinc Coordination Compounds of an Asymmetric Bidentate Schiff Base

Montazerozohori

Hoseinpour

Naghiha

et al. 2015

Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-

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“…Thermogravimetric studies can also be supported by X-ray crystallography, infrared and DTA studies so that possible modes of dehydration and decomposition can be established. When the thermogravimetry is used in association with other physicochemical techniques, its field of application widens and provides a clear geometry for the complexes [6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Thermal analyses and spectral characterization of some synthesized metal(II) Schiff base complexes

Jain

Mishra

Gupta

2012

J Therm Anal Calorim

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Schiff base metal complexes derived from 2-thiophenecarboxylidine-4-anisidine, 3,4-dihydroxy-5-nitrobenzylidine-2-amino-5-methylthiazole and 3,4-dihydroxy-5-nitrobenzylidine-4-chloroaniline have been synthesized and characterized by elemental analysis, IR, UV-Vis, molar conductance and thermal analyses. The complexes are coloured and stable in air at room temperature. The complexes exhibit coordination number to be 4 and 6. The thermal behaviour of metal complexes shows that the hydrated complexes lose water molecules of hydration in the first and then is immediately followed by decomposition of ligand molecules in the subsequent steps.

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“…Many symmetrical tetradentate Schiff bases of diamines with aldehydes and ketones have been prepared and studied intensively. However, less attention has been focused on unsymmetrical tetradentate Schiff bases derived from diamines with different aldehydes and ketones [25][26][27].…”

Section: Introductionmentioning

confidence: 99%

Synthesis, spectroscopic characterization, and 3D molecular modeling of lead(II) complexes of unsymmetrical tetradentate Schiff-base ligands

Singh

2011

Res Chem Intermed

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Solid complexes of Pb(II) with unsymmetrical Schiff-base ligands (H 2 L) derived from 2-aminobenzophenone, thiosemicarbazide, semicarbazide, salicylaldehyde, 2-hydroxynaphthaldehyde, and o-hydroxyacetophenone have been synthesized and characterized by elemental analysis, conductance measurements, molecular weight measurement, and UV-Vis, FTIR, 1 H NMR, and 13 C NMR spectroscopy. The spectral studies suggest the ligands behave as dibasic tetradentate ligands with ONNO/ONNS donor atom sequences toward the central metal ion. From the microanalytical data, the stoichiometry of the complexes was found to be 1:1 (metal:ligand). The physicochemical data suggest a tetracoordinated environment around the metal ion. Three-dimensional molecular modeling and analysis of bond lengths and bond angles have also been conducted for a representative compound, [PbL 1 ], to substantiate the proposed structures.

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Synthesis and spectroscopic characterization of new tetradentate Schiff base and its coordination compounds of NOON donor atoms and their antibacterial and antifungal activity

Cited by 93 publications

References 28 publications

Synthesis, Characterization, and Antibacterial Activities of Some New Zinc Coordination Compounds of an Asymmetric Bidentate Schiff Base

Synthesis, Characterization, and Antibacterial Activities of Some New Zinc Coordination Compounds of an Asymmetric Bidentate Schiff Base

Thermal analyses and spectral characterization of some synthesized metal(II) Schiff base complexes

Synthesis, spectroscopic characterization, and 3D molecular modeling of lead(II) complexes of unsymmetrical tetradentate Schiff-base ligands

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