Synthesis and spectroscopic characterization of new solid solution containing Mg(II) and Cu(II) complexes with hexadentate 1,3-propanediaminen, N,N’,N’-tetraacetate (1,3-pdta) ligand: In vitro antifungal activity of 1,3-pdta-Cu(II) complexes

Abstract

New solid solution containing Mg(II) and Cu(II) complexes with hexadentate 1,3-propanediamine-N,N,N?,N?-tetraacetate ligand (1,3-pdta), [Mg(H2O)6] [Mg0.5Cu0.5(1,3-pdta)].2H2O was synthesized and structurally characterized by elemental microanalyses, molar conductivity, and spectroscopic (IR and UV-Vis) measurements. The spectroscopic data of [Mg(H2O)6][Mg0.5Cu0.5(1,3-pdta)].2H2O were compared with those for [Mg(H2O)6][Cu(1,3-pdta)].2H2O complex of the known molecular structure determined by single-crystal X-ray diffraction analysis. In vitro growth inhibition activity of [Mg(H2O)6][Mg0.5Cu0.5(1,3-pdta)].2H2O and [Mg(H2O)6][Cu(1,3-pdta)].2H2O against Colletotrichum acutatum and their effects on this fungus sporulation level are investigated. The obtained results showed that the highest percentage of inhibition for mycelium growth was achieved at a concentration of 500 ?g/mL for the investigated complexes. The biological activities of the investigated complexes were compared with those for the commercial formulation of fungicide captan (Method 480 SC).