Synthesis and Spectroscopic Characterization of New Lead(II) Thiosaccharinates. Molecular Structure of Bis(thiosaccharinato)tetrakis(pyridine)dilead(II) and Thiosaccharinato‐bis(1,10‐phenantroline)lead(II) Thiosaccharinate

Abstract

Four new lead(II) thiosaccharinate complexes: [Pb(tsac)2H2O] (1) (tsac: thiosaccharinate anion), [Pb2(tsac)4(py)4] (2) (py: pyridine), [Pb(tsac)(o‐phen)2](tsac)·CH3CN (3) (o‐phen: 1,10‐phenantroline), and [Pb(tsac)2(bipy)] (4) (bipy: 2,2′‐bipyridine) were prepared. The infrared and electronic spectra as well as the thermal analysis of all the compounds were recorded and discussed. The thiosaccharinate anion acts in three different coordination forms, one of then reported for the first time. The crystal structures of complexes 2 and 3 have been determined by single crystal X‐ray diffractometry. In complex 2, two monomeric moieties are joined together forming a symmetric bis‐μ‐sulphur bridged dimer by interaction of two lead(II) atoms through the exocyclic sulphur atoms of two thiosaccharinate ligands. The seven‐fold coordination sphere of each lead atom is completed by two pyridine nitrogen atoms and by another sulfur and two nitrogen atoms of the thiosaccharinate anions. In complex 3, the lead(II) atom is coordinated by four nitrogen atoms of two 1,10‐phenantroline molecules and by the sulfur and nitrogen atoms of one thiosaccharinate ion. The second anion has an electrostatic interaction with the nucleus.

Bismuth(III) Saccharinate and Thiosaccharinate Complexes and the Effect of Ligand Substitution on Their Activity against Helicobacter pylori

“…In contrast to 1 , where bismuth bonds to the saccharinate ligand through the imino N – , the replacement of the carbonyl O with S leads to 2 being classed as a bismuth thiolate, with formal attachment to the ligand being through the Bi–S exo σ-bond. This is not surprising given the thiophilic nature of bismuth and earlier evidence from structural reports on a series complexes with Pb(II). , The Bi(1)–S(1) bond distance of 2.6399(7) Å is typical for bismuth thiolates, − while the sulfonyl O(1)–Bi(1) distance of 2.890(2) Å is significantly longer than in 1 and is comparable with that observed in [(PhSO 2 t Bu) 2 Bi(Tol)], 2.914(6) Å . The imine double bond in 2 , N(1)–C(13), is 1.303(3) Å, while C(13)–S(2) is 1.719(3) Å and displays single-bond character.…”

“…The imine double bond in 2 , N(1)–C(13), is 1.303(3) Å, while C(13)–S(2) is 1.719(3) Å and displays single-bond character. These can be compared with the analogous bonds in [Pb 2 (tsac) 4 (py) 4 ], which show similar bond distances of 1.321(17) and 1.699(14) Å, respectively, and can be contrasted with those in the crystal thione form of thiosaccharin, which are 1.384(4) and 1.622(6) Å, respectively …”

The Importance of Heterolepticity in Improving the Antibacterial Activity of Bismuth(III) Thiolates

“…2.581 Å). The C–S [S(1)–C(1) 1.726(6), S(5)–C(19) 1.728(6) and S(3)–C(9) 1.687(6) Å] and C–N bond lengths [N(1)–C(1) 1.310(7), N(2)–C(10) 1.315(7) and N(3)–C(19) 1.301(8) Å] have single‐bond character and are comparable with the reported values [S–C 1.699(14) and C–N 1.309(12) Å] . All the ligands form four‐membered metallacyclic rings due to chelation through the N and S donor atoms with small bite angles [S(1)–Bi(1)–N(1) 59.35(10), S(3)–Bi(1)–N(2) 58.37(10) and S(5)–Bi(1)–N(3) 58.70(12)°].…”

Synthesis and Structural Analysis of New Palladium(II) Thiosaccharinates with Triphenylphosphane or Diphosphanes

“…In the last years, we reported mono‐ and poly‐nuclear structures of Ag I , Pb II , Cu I , and Cd II thiosaccharinates 12. As was already reported, the thiosaccharinate anion can coordinate metal atoms through the endocyclic nitrogen and/or the hexocyclic sulfur atoms, therefore acting with a great variety of coordination modes 12d.…”