Synthesis and spectroscopic analysis of Schiff Bases of Imesatin and Isatin derivatives

Oguntoye, O.S.; Hamid, Abdulmumeen A.; Iloka, Gabriel S.; Bodede, Olusola; Owalude, Samson O.; Tella, Adedibu C.

doi:10.4314/jasem.v20i3.20

Cited by 9 publications

(6 citation statements)

References 9 publications

(8 reference statements)

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“…The FT-IR spectrum of all synthesized compounds show characteristic bands at 3354-3400, 3149-3277, 1680-1720 cm -1 and a weak broad band in 1611-1673 cm -1 region, which can be assigned respectively to -NH2, N-H (isatin), C=O and C=N (azomethine linkage) vibrations of 3-hydrazinoindolin-2-one 3 [6,15,16]. This is a direct evidence of the condensation of hydrazine hydrate 2 on the carbonyl in position 3 of isatin 1 and confirms the formation of the de-sired Schiff bases.…”

Section: Infrared Spectroscopy (Ft-ir)mentioning

confidence: 96%

Isatin Aldazines Synthesis using A Proton Exchanged Algerian Montmorillonite Clay as Acid Eco-friendly Catalyst

Benlahreche

Taleb

Lahrech

et al. 2019

Bull. Chem. React. Eng. Catal.

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An efficient and easy procedure is developed for the synthesis of isatin aldazines or bis-Schiff bases of isatin, catalyzed by a proton exchanged Algerian montmorillonite clay (MMT-H + ) as green catalyst. The products were obtained in two catalyzed steps under conventional heating in ethanol. Isatin-3hydrazone obtained from the reaction of isatin with hydrazine monohydrate reacts in the second step with the appropriate aromatic aldehydes to give the desired products in good yields. The main advantages of using this protonated solid non-toxic catalyst in this synthesis are its availability and low cost, the simplicity of its use, the recycling possibilities without significant loss of its catalytic activity and its environmentally benign process. ] and also considered as corrosion inhibitors [20]. Synthesis of isatin-based azines are generally made by condensation of 3-hydrazinoindolin-2-one with aldehydes or ketones to yield respectively isatin aldazines (R1 or R2 = H) or isatin ketazines (R1 and R2 ≠ H) [21]. Most of these synthesis are based mainly on traditional thermal methods in presence of organic solvents and a range of catalysts, such as: acetic acid [22], HCl [23], triethyl amine [24], FeCl3.6H2O [25],

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Section: Infrared Spectroscopy (Ft-ir)mentioning

confidence: 96%

Isatin Aldazines Synthesis using A Proton Exchanged Algerian Montmorillonite Clay as Acid Eco-friendly Catalyst

Benlahreche

Taleb

Lahrech

et al. 2019

Bull. Chem. React. Eng. Catal.

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“…The electronic spectrum of the ligand exhibited strong absorption at 314nm and 331nm that are attributed to (π→π * ), (n→π * ) respectively 11 . The electronic spectrum of Ni(II) complex showed three peaks at 987, 598, and 449 nm assigned to 3 A2g→ 3 T2g(F) 3 A2g→ 3 T1g(F) and 3 A2g→ 3 T1g(P) respectively 12 . Ni(II) complex magnetic moment value were equal to (2.8)B.M, which confirmed its high spin octahedral geometry ,Table 2.…”

Section: Uv-visible For the Ligand And Its Complexesmentioning

confidence: 99%

“…Measurements of conductivity reveal electrolyte dynamics 15 . According to Table 2, all of the complexes have octahedral geometry [11][12][13][14] . Table 3 contains a complete list of the electronic spectra's data.…”

Section: Uv-visible For the Ligand And Its Complexesmentioning

confidence: 99%

Synthesis, Spectroscopy and Biological Activity Study of Some New Complexes with Schiff Base Derived From Malonic Acid Dihydrazide with 2-pyridine Crboxaldehyde

Hammoda,

Shaalan

2024

Baghdad Sci.J

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From synthesized novel ligand (L) made of Malonic acid dihydrazide and 2-pyridine carboxaldehyde, new complexes have been created. Ni(II), Cu(II), and Zn(II) complexes were created as a result. FT-IR, UV-Vis, Mass, 1H-NMR, 13C-NMR, C.H.N., Chloride-containing, Molar Conductance, Magnetic Susceptibility, and Atomic Absorption have all been used to identify these compounds. For each Nickel, Copper, and Zinc complexes the characterization findings revealed complexes with hexadentate octahedral coordination geometry and tetradentate ligand. Two Gram-positive (Staphylococcus aureus and Bacillus subtitles) and two Gram-negative (Escherichia coli and Pseudomonas aeruginosa) bacteria, as well as candida fungus, were evaluated for the biological activities of the novel compounds. With the exception of the Nickel complex, which failed to produce any effective inhibitory effects against pseudomonas, their results in inhibition were good.

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“…The first band is attributed to aromatic (π-π*) transition, second band is assigned to azomethine group (n-π*) transition and third band involves charge transfer within the N-methylisatin moiety. [44][45][46] In the spectra of aryltellurium(IV) complexes, all these transitions were shifted to higher wavelength indicating the coordination of azomethine nitrogen and oxygen atoms to the tellurium metal.…”

Section: Uv-vis Spectramentioning

confidence: 99%

Synthesis, Spectroscopic, Biological Activity, Molecular Docking and Density Functional Theoretical Investigations of Novel Tellurium(IV) Schiff Base Complexes

et al. 2021

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Aryltellurium(IV) complexes (3a-3f) of type RTeCl 3 .NMeIAP and R 2 TeCl 2 .NMeIAP (R belongs to 4-Hydroxyphenyl, 4-Methoxyphenyl and 3-Methy-4-hydroxyphenyl) have been synthesized from 3-((2-Hydroxyphenyl)imino)-1-methylindolin-2-one Schiff base ligand (NMeIAP or HL), prepared by the condensation of N-methylisatin and o-aminophenol in 1 : 1 molar ratio. The synthesized Schiff base and its aryltellurium(IV) complexes were characterized by molar conductance, FT-IR, elemental analyses, SEM analyses, powder X-ray diffraction, 1 H NMR, 13 C NMR, UV-Vis, mass spectrometry, DFT studies and thermogravimetric (TG) analysis. The stoichiometry of the compounds and the percentages of the different elements present in all compounds were confirmed by the elemental analysis. The Schiff base ligand behaved as a monobasic tridentate ONO chelating agent. The molecular structures of the ligand (NMeIAP) and its complexes were optimized theoretically and their electronic properties such as HOMO and LUMO energies were determined by def2-SVP calculations. Molecular docking studies was used to determine probable and effective binding modes between ligand and different active sites of the receptors. X-ray diffraction revealed the crystalline nature of the Schiff base whereas the complexes are semi crystalline in nature. NMeIAP and aryltellurium(IV) complexes were tested against bacteria: B. cereus and X. campestris. Antifungal activity was determined against C. albicans, F. oxysporum and S. sclerotium.

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Synthesis and spectroscopic analysis of Schiff Bases of Imesatin and Isatin derivatives

Cited by 9 publications

References 9 publications

Isatin Aldazines Synthesis using A Proton Exchanged Algerian Montmorillonite Clay as Acid Eco-friendly Catalyst

Isatin Aldazines Synthesis using A Proton Exchanged Algerian Montmorillonite Clay as Acid Eco-friendly Catalyst

Synthesis, Spectroscopy and Biological Activity Study of Some New Complexes with Schiff Base Derived From Malonic Acid Dihydrazide with 2-pyridine Crboxaldehyde

Synthesis, Spectroscopic, Biological Activity, Molecular Docking and Density Functional Theoretical Investigations of Novel Tellurium(IV) Schiff Base Complexes

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