Synthesis and spectral studies of some alkyl [(substituted phenylsulfonyl)methyl]benzoate derivatives. 3

Abstract

The synthesis, IR spectra, and proton NMR spectra of some alkyl [(substituted phenylsulfonyl)methyl]benzoate derivatives are reported.

Palladium Catalyzed Monoselective α-Arylation of Sulfones and Sulfonamides with 2,2,6,6-Tetramethylpiperidine·ZnCl·LiCl Base and Aryl Bromides

“…9, 166.0 ppm; MS (EI): m / z (%) = 318 [M] + (5), 273 (5), 254 (1), 209 (2), 182 (1), 163 (100), 135 (20), 107 (20); IR: υ = 2916 (w), 1710 (s), 1276 (s), 1148 (s) 1113 (s) 1086 (m), 1020 (m), 820 (m), 777 (m), 708 (s) cm –1 . The obtained data match those reported in the literature …”

“…The obtained data match those reported in the literature 34. 4-(Tosylmethyl)benzonitrile (6aj) [CAS: 59475-60-4].…”

“…The obtained data match those reported in the literature. 34 4-(Tosylmethyl)benzonitrile (6aj) . The compound was prepared according to method B from p-tolyl methyl sulfone (85.1 mg, 0.50 mmol), 4-bromobenzonitrile (109 mg, 0.60 mmol), Pd(dba) 2 (28.8 mg, 0.05 mmol), XPhos (25.1 mg, 0.05 mmol), and tmp•ZnCl•LiCl solution (2.5 M, 1.25 mmol, 5.0 mL).…”

Synthesis of Sulfones by Iron‐Catalyzed Decomposition of Sulfonylhydrazones

“…Methyl 4‐[( p ‐tolylsulfonyl)methyl]benzoate (6d): 19 Methyl 4‐[(2‐tosylhydrazono)methyl]benzoate (60.8 mg, 0.3 mmol) afforded 6d (44.3 mg, 40 % yield) as a yellow solid (m.p. 179.0–198.5 °C, decomposition).…”