Synthesis and Selected Transformations of New 2‐Aminopyridine Derivatives Based on Furan‐2(5H)‐ones
Robert M. Hakobyan,
Astghik A. Shahkhatuni,
Hovhannes S. Attaryan
et al.
Abstract:Compounds with γ‐lactone fragments, as well as derivatives of 2‐aminopyridines and 2‐aminopyridons, are biologically active, and some of them are used as drugs. The condensed combination of γ‐lactones with 2‐aminopyridones, such as the natural alkaloid cerpegin, has a wider spectrum of biological activities. Here we combined γ‐lactone and 2‐aminopyridine derivatives into one molecule via a single bond. A series of such compounds were synthesized in high yields through the transformations of unsaturated furan‐2… Show more
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