The 1,3,4‐thiadiazole‐enaminone (I), synthesized via reaction of the corresponding benzamide with DMF‐DMA, is used as precursor in syntheses of a wide variety of new heterocyclic compounds, including 5‐substituted‐1,3,4‐thiadiazole, hydrazone, pyrazolotriazine, and 1,2,4‐triazolotriazine derivatives.