Synthesis and reactivity of cyclometallated platinum (II) compounds containing [C,N,N′] terdentate ligands: Crystal structures of [PtCl{(CH3)2N(CH2)3NCH(4-ClC 6H3)}], [PtCl{(CH3)2N(CH2)3NCH(2-ClC6H3)}] and [PtCl{(CH3)2N(CH2)3NCH(3-(CH3)C6H3)}]

Cyclopalladated and cycloplatinated benzophenone imines: Antitumor, antibacterial and antioxidant activities, DNA interaction and cathepsin B inhibition

“…31P-{1H} NMR of compound 5 produced a singlet at 22.64 ppmwith the expected satellites for 195Pt with a coupling constant between 31P and 195Pt of 4068 Hz, and the 195Pt-{1H} NMR produced a doublet at −4206.6 ppm with a coupling constant between 31P and 195Pt of 4068 Hz. These chemical shifts for 31P and 195Pt and coupling constant between 31P and 195Pt were quite similar to those previously reported for compounds of formula trans-N,P-[Pt(C,N)Cl(PPh3)], being (C,N) an orthocycloplatinated benzalimine or cycloplatinated ferrocenylimine with the iminic bond included in the metalacycle [49,50].…”

“…The triphenylphosphane ligand is in trans position to the iminic nitrogen atom, in accordance with the trans-N,P configuration proposed for compound 5 by NMR. Distances and angles around the platinum(II) center are between the normal intervals [50], being the C(13)-Pt(1)-N(1) [79.80(5)°] and C(13)-Pt(1)-Cl(1) [167.74(4)°] those that deviated most fromthe ideal angles for a square planargeometry (90 and 180°). The atoms coordinated to the platinum(II) center (Cl1, P1, C13 and N1) were almost in a plane and the metalacycle (Pt1, C13, C8, C1 and N1) was practically planar.…”

Luminescence studies of new [C,N,N′] cyclometallated platinum(ii) and platinum(iv) compounds

“…Alternatively, the corresponding [N,N']-chelate complex can be isolated and such complexes further react to yield cycloplatinated derivatives via C-H activation (see scheme 1). [11][12][13][14] These reactions generally require prolonged reaction times and give moderate yields. In the present study, compound For the latter, as previously observed for analogous cyclometallated compounds 11,12 and in agreement with the flexibility of the ligands derived from propylenediamine, the chelate angle N(1)-Pt-N(2) increases up to 95.8(3)º. .…”

“…[11][12][13][14] These reactions generally require prolonged reaction times and give moderate yields. In the present study, compound For the latter, as previously observed for analogous cyclometallated compounds 11,12 and in agreement with the flexibility of the ligands derived from propylenediamine, the chelate angle N(1)-Pt-N(2) increases up to 95.8(3)º. . According to previously reported procedures, [18][19] iodobenzene dichloride was used in the synthesis of 3a to avoid the handling of Cl2 gas.…”

Racemic (RSC,SRS)-(2-{[1-allyloxycarbonyl-3-(methylsulfanyl)propyl]iminomethyl}phenyl-κ3S,N,C1)chloridoplatinum(II)

“…For cyclometallated Pt II complexes having terdentate benzylidenamine ligands cyclometallated benzylideneamine, see: Capapé et al (2005); Caubet et al (2003); Riera et al (2000). For organometallic amino acid complexes, see: Severin et al (1998).…”